supported by the National Key R&D Program of China(nos.2019YFA0904200 and 2018YFA0507600);the Tsinghua University Spring Breeze Fund(no.2020Z99CFY042);the National Natural Science Foundation of China(nos.92053108 and 31961143004);NCC Fund(no.NCC2020FH04).
Stimulator of interferon genes,namely STING,an adaptor protein located in the endoplasmic reticulum,has been recognized as a shining target for cancer and infection research.However,STING agonists cyclic dinucleotides...