AZOLE

作品数:47被引量:35H指数:3
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相关领域:理学医药卫生更多>>
相关作者:周成合马尔妮王建华王露茜彭燕琼更多>>
相关机构:西南大学北京林业大学江苏丘陵地区镇江农业科学研究所江苏农林职业技术学院更多>>
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相关基金:国家自然科学基金重庆市自然科学基金国家教育部博士点基金国家重点基础研究发展计划更多>>
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  • 学科=医药卫生—药学x
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Two natural molecules preferentially inhibit azole-resistant Candida albicans with MDR1 hyperactivation被引量:1
《Chinese Journal of Natural Medicines》2019年第3期209-217,共9页SHI Hong-Zhuo CHANG Wen-Qiang ZHANG Ming LOU Hong-Xiang 
funded by the National Natural Science Foundation(Nos.81630093,81773786,81402804);the Young Scholars Program of Shandong University
Antifungal drug resistance is a significant clinical problem, and antifungal agents that can evade resistance are urgently needed. In infective niches, resistant organisms often co-existed with sensitive ones, or a su...
关键词:CANDIDA ALBICANS MDR1 AZOLE resistance CO-CULTURE 
Synthesis and anti-inflammatory activity of 2-substituted-((N,N-disubstituted)-1,3-benzoxazole)-5-carboxamides被引量:1
《药学学报》2010年第6期730-734,共5页Reena M kiran G Rajyalakshmi G Venkateshwa Rao J Sarangapani M 
A series of 2-substituted-((N,N-disubstituted)-1,3-benzoxazole)-5-carboxamides derivatives were synthesized by the reaction of 2-substituted-5-carbomethoxy benzoxazole with different secondary amines.The newly synthes...
关键词:BENZOXAZOLE anti-inflammatory activity CARRAGEENAN 
Design, Synthesis and Biological Evaluation of Non-azole Inhibitors of Lanosterol 14α-Demethylase of Fungi被引量:1
《Chinese Chemical Letters》2006年第9期1189-1192,共4页Bin YAO You Jun ZHOU Jü ZHU Jia Guo Lü Yao Wu LI Jun CHENG Qing Feng JIANG Can Hui ZHENG 
supported by the National Natural Science Foundation of China(No.30572257)
Novel tetralin compounds were designed and synthesized on the three-dimensional model of lanosterol 14α-demethylase of Candida albicans. All of the lead compounds exhibited potent antifungal activities, especially co...
关键词:ANTIFUNGAL 2-aminotetralins lanosterol 14α-demethylase inhibitor. 
Synthesis of a Photolabeling Probe for the Study of Antiviral Mechanism of Ribavirin被引量:1
《Chinese Chemical Letters》2004年第8期907-910,共4页QiongYouwu XunZHU JinQiaoWAN FanQiQU LingPENG 
Ribavirin has been used in urgency to treat SARS patients recently. In order to study its antiviral mechanism by photolabeling approach, we have synthesized and characterized 5-azido-1-β-D-ribofuranosyl-1,2,4-triazol...
关键词:RIBAVIRIN photolabeling probe of ribavirin azidotriazole nucleoside azole nucleosides photolabeling. 
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