CO-CULTURE

作品数：146被引量：435H指数：10
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相关领域：医药卫生生物学更多>>
相关作者：王宇琛李宁刘放徐璐璐吴雄文更多>>
相关机构：华中科技大学第二军医大学中国人民解放军总医院南开大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金天津市自然科学基金更多>>
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Label-free and rapid mechanics of single cells under high-density co-culture conditions by deep learning image recognition-assisted atomic force microscopy
《Acta Biochimica et Biophysica Sinica》2025年第2期317-320,共4页Xuliang Yang Mi Li 
supported by the grants from the National Natural Science Foundation of China(No.62273330);the Key Research Program of Frontier Sciences CAS(No.ZDBS-LY-JSC043).
Mechanical cues play an important role in regulating cellular activities.Cells are able to sense and respond to the mechanical cues present in the extracellular physical microenvironment via mechanotransduction[1],whi...
关键词：ORGANS CULTURE dimensions 
Co-culture models for investigating cellular crosstalk in the glioma microenvironment
《Cancer Pathogenesis and Therapy》2024年第4期219-230,共12页Xiaodong Niu Yan Zhang Yuan Wang 
Glioma is the most prevalent primary malignant tumor in the central nervous system(CNS).It represents a diverse group of brain malignancies characterized by the presence of various cancer cell types as well as an arra...
关键词：GLIOMA Coculture techniques Tumor microenvironment 
Saccharomyces cerevisiae and Kluyveromyces marxianus yeast co-cultures modulate the ruminal microbiome and metabolite availability to enhance rumen barrier function and growth performance in weaned lambs
《Animal Nutrition》2024年第4期139-152,共14页Zixuan Xu Lan Yang Hui Chen Shixiong Liu Xueqiang Li Songjian Li Chun Ying Xiao Li Rui Du Dacheng Liu 
supported by the National Key Research and Development Program of China(2023YFE0100400);National Natural Science Foundation of China(32060774);Science and Technology Project of Inner Mongolia Autonomous Region(2020GG0036);Basic Scientific Research Business Project of Universities directly under the Inner Mongolia Autonomous Region(BR22-11-17).
In lambs,weaning imposes stress that can contribute to impaired rumen epithelial barrier functionality and immunological dysregulation.In this study,the effects of a yeast co-culture consisting of Saccharomyces cerevi...
关键词：Weaned lamb Rumen bacteria CO-CULTURE Metabolic profile Rumen function 
Co-culture of natural killer cells and tumor spheroids on a heterogeneous multilayer paper stack
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2024年第12期1097-1107,共11页Yuanyuan XIE Xiaoyan YANG Rong PAN Lixia GAO Ling YU 
supported by the National Natural Science Foundation of China(No.32171401);the Natural Science Foundation of Chongqing(Nos.CSTB2022NSCQ-MSX0808 and cstc2021jcyj-bsh0239);the Innovation Platform for Academicians of Hainan Province(No.YSPTZX202126),China。
Multilayer paper-based cell culture,as an in vitro three-dimensional(3D)cell culture method,has been frequently used to research drug bioavailability,therapeutic efficacy,and dose-limiting toxicity in malignant tumors...
关键词：Multilayer paper stack CO-CULTURE Tumor spheroid Human umbilical vein endothelial cell(HUVEC) Natural killer cell(NK cell) Migration 
Experimental study on contact co-culture of DiI labeled rat bone marrow mesenchymal stem cells and neonatal rat cardiomyocytes on polycaprolactone film to make myocardial patch
《China Medical Abstracts(Internal Medicine)》2024年第3期166-166,共1页ZHANG Zichang 
Objective To investigate the possible mechanism of Dil labeled bone marrow mesenchymal stem cells(BMSCs) in contact co-cultured with neonatal rat cardiomyocytes(CMs) on polycaprolactone(PCL) film to make myocardial pa...
关键词：NEONATAL PATCH MARROW 
Gut microbial interactions based on network construction and bacterial pairwise cultivation被引量：1
《Science China(Life Sciences)》2024年第8期1751-1762,共12页Min-Zhi Jiang Chang Liu Chang Xu He Jiang Yulin Wang Shuang-Jiang Liu 
supported by the National Key Research and Development Program of China(2021YFA0717002);Taishan Young Scholars(tsqn202306029).
Association networks are widely applied for the prediction of bacterial interactions in studies of human gut microbiomes.However,the experimental validation of the predicted interactions is challenging due to the comp...
关键词：human gut microbiome gut microbial pairwise interaction CO-CULTURE association network microbial community 
Effect of rice cultivar on greenhouse-gas emissions from rice-fish co-culture
《The Crop Journal》2024年第3期888-896,共9页Kexin Xie Mengjie Wang Xiaodan Wang Fengbo Li Chunchun Xu Jinfei Feng Fuping Fang 
supported by the National Natural Science Foundation of China(42177455);“Pioneer”and“Leading Goose”R&D Program of Zhejiang(2022C02008 and 2022C02058);Central Public-interest Scientific Institution Basal Research Fund(CPSIBRF-CNRRI-202305);the Agricultural Science and Technology Innovation Program(ASTIP)。
In aquaculture,co-culturing rice with fish may mitigate greenhouse-gas emissions.In this study,co-culture of four rice cultivars in a laboratory-scale rice–fish system reduced CH_(4)and N_(2)O emissions relative to f...
关键词：Greenhouse gas emissions AQUACULTURE Rice-fish system Rice cultivar 
Optimized collision energy based multiple reaction monitoring facilitated validation of immune cell activated proteins in 3D cancer-Immune cell co-culture model
《LabMed Discovery》2024年第2期89-94,共6页Rajdeep Chakraborty Thiri Zaw 
supported by Australian and New Zealand Head and Neck Cancer Society Trudi Shine Adenoid Cystic Carcinoma Grant Award 2021.
Objective:Multiple reaction monitoring(MRM),is a highly sensitive targeted mass spectrometry technique that is used to validate discovery phase mass spectrometry data.Through this simple technique,relative protein exp...
关键词：Multiple reaction monitoring Biomolecular detection Salivary gland cancer Immune evasion Adenoid cystic carcinoma 
Enhancement of polymyxin B1 production by an artificial microbial consortium of Paenibacillus polymyxa and recombinant Corynebacterium glutamicum producing precursor amino acids被引量：1
《Synthetic and Systems Biotechnology》2024年第1期176-185,共10页Hui-Zhong Sun Si-Yu Wei Qiu-Man Xu Wei Shang Qing Li Jing-Sheng Cheng Ying-Jin Yuan 
grateful for the financial supports from the National Key R&D Program of China(2018YFA0902200);the National Natural Science Foundation of China(Program:21878224).
Polymyxin B,produced by Paenibacillus polymyxa,is used as the last line of defense clinically.In this study,exogenous mixture of precursor amino acids increased the level and proportion of polymyxin B1 in the total of...
关键词：POLYMYXIN CO-CULTURE Paenibacillus polymyxa Corynebacterium glutamicum Medium optimization Metabolic precursors 
New Antibacterial Dihydropyrones Induced by Co-Culture of Penicillium crustosum PRB-2 and Penicillium citrinum HDN11-186
《Journal of Ocean University of China》2024年第1期216-220,共5页YU Guihong ZHOU Luning WU Guangwei LI Dehai 
supported by the National Natural Science Foundation of China(No.41806167);the High-Level Talents Research Fund of Qingdao Agricultural University(No.665/1120034);the NSFC-Shandong Joint Fund(No.U1906212);the Major Project of the 14th Five-Year Plan(No.2022QNLM030003-1);the Natural Science Foundation of Shandong Province(No.ZR2021ZD28);the Hainan Provincial Joint Project of Sanya Yazhou Bay Science and Technology City(No.2021CXLH0012);the Youth Innovation Plan of Shandong Province(No.2019KJM004).
Two new dihydropyrones,rhytismatones C(1)and D(2),and a known compound,penicillenol A1(3),were isolated from the co-culture broth of the deep-sea-derived fungus Penicillium crustosum PRB-2 and Suaeda salsa-derived end...
关键词：CO-CULTURE Penicillium crustosum Penicillium citrinum dihydropyrones antibacterial activity 
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