NEFERINE

作品数：19被引量：87H指数：6
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相关领域：医药卫生更多>>
相关作者：钱家庆徐智李青曹宏宇郭治彬更多>>
相关机构：中南大学华中科技大学江西医学院第一附属医院南华大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Journal of Chinese Pharmaceutical Sciences》《Acta Biochimica et Biophysica Sinica》更多>>
相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划广东省自然科学基金更多>>
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Neferine inhibits the progression of diabetic nephropathy by modulating the miR-17-5p/nuclear factor E2-related factor 2 axis被引量：3
《Journal of Traditional Chinese Medicine》2024年第1期44-53,共10页HUANG Hongmei YANG Maojun LI Ting WANG Dandan LI Ying TANG Xiaochi YUAN Lu GU Shi XU Yong 
the Chengdu Health and Wellness Commission:Exploring the Mechanism of Neferine on Diabetic Nephropathy Based on mi R-17/Nrf2 Axis(No.2021127)。
OBJECTIVE:To investigate the effect of Neferine(Nef)on diabetic nephropathy(DN)and to explore the mechanism of Nef in DN based on miRNA regulation theory.METHODS:A DN mouse model was constructed and treated with Nef.S...
关键词：diabetic nephropathies NEFERINE miR-17-5p NF-E2-related factor 2 oxidative stress 
Development of a cell-based HTS adaptable calcium fluorescent assay in FlexStation3 for the screening of TRPV3 inhibitors
《Journal of Chinese Pharmaceutical Sciences》2017年第9期675-683,共9页Xiaomei Sun Ningning Wei Xiaoying Sun Kewei Wang 
The National Natural Sciences Foundation of China(Grant No.81573410);the Ministry of Science and Technology of China(Grant No.2014ZX09507003-006-004);the Natural Sciences Foundation of Shandong Province(Grant No.ZR2015QL008)
To develop a cell-based high-throughput calcium fluorescent assay for screening of TRPV3 channel modulators, we employed the FlexStation3 microplate reader and optimized conditions of the high-throughput screening （...
关键词：TRPV3 inhibitor NEFERINE FlexStation3 Whole-cell patch clamp CALCIUM 
Inhibitory Effects of Neferine on Na_v1.5 Channels Expressed in HEK293 Cells被引量：2
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2016年第4期487-493,共7页王琛 王换 肖军花 王嘉陵 向继洲 汤强 
Neferine, a bisbenzylisoquinoline alkaloid in Lotus Plumule, was proved to have a wide range of biological activities. In the present study, using whole-cell patch-clamp technique, we investigated the effects of nefer...
关键词：NEFERINE Nay1.5 channel whole-cell patch-clamp HEK293 cells 
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