SYNERGIST

作品数:25被引量:35H指数:4
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相关领域:医药卫生更多>>
相关作者:徐优张艺萱王良宋萍李娜更多>>
相关机构:台湾大学屏东科技大学四川大学河北农业大学更多>>
相关期刊:《Petroleum Science》《Asian Pacific Journal of Tropical Biomedicine》《Plant Diseases and Pests》《American Journal of Analytical Chemistry》更多>>
相关基金:国家自然科学基金中国博士后科学基金国家科技支撑计划更多>>
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Synergistic engineering of CRISPR-Cas nucleases enables robust mammalian genome editing被引量:4
《The Innovation》2022年第4期74-82,共9页Yangcan Chen Yanping Hu Xinge Wang Shengqiu Luo Ning Yang Yi Chen Zhikun Li Qi Zhou Wei Li 
supported by the National Key Research and Development Program(2019YFA0110800 and 2020YFA0707900 to W.L.and 2018YFA0108400 and 2019YFA0903800 to Q.Z.);the Strategic Priority Research Programof the Chinese Academy of Sciences(XDA16030403 to W.L.);the National Natural Science Foundation of China(31621004 to Q.Z.and W.L.);and the CAS Project for Young Scientists in Basic Research(YSBR-012 to W.L.).
The naturally occurring prokaryotic CRISPR-Cas systems provide valuable resources for the development of new genome-editing tools.However,the majority of prokaryotic Cas nucleases exhibit poor editing efficiency in ma...
关键词:EDITING engineering MAMMALIAN 
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