PRION

作品数:173被引量:154H指数:5
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相关作者:朱钦士赵德明周筠梅练富林柯莎更多>>
相关机构:中国农业大学中国科学院南加州大学厦门大学更多>>
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  • 期刊=Cell Researchx
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Prion-like behavior of MAVS in RIG-I signaling被引量:3
《Cell Research》2011年第12期1643-1645,共3页Eva Marie Y Moresco Diantha La Vine Bruce Beutler 
Viral infection triggers the innate antiviral response in part through acti- vation of RIG-I, a cytoplasmic sensor of 5'-triphosphorylated and uncapped single- or double-stranded RNA, which are not found among endoge...
关键词:朊病毒 双链RNA 信令 行为 信号蛋白 转录激活 病毒感染 先天免疫 
PrP^C-related signal transduction is influenced by copper, membrane integrity and the alpha cleavage site被引量:4
《Cell Research》2009年第9期1062-1078,共17页Cathryn L Haigh Victoria A Lewis Laura J Vella Colin L Masters Andrew F Hill Victoria A Lawson Steven J Collins 
The copper-binding, membrane-anchored, cellular prion protein (PrP~) has two constitutive cleavage sites producing distinct N- and C-terminal fragments (N1/C1 and N2/C2). Using RK13 cells expressing either human P...
关键词:PRION COPPER endoproteolytic cleavage signal transduction lipid raft 
The saga of prion: to cut or not to cut
《Cell Research》2009年第9期1039-1040,共2页Man-Sun Sy 
Transmissible Spongiform Encephalopathies (TSE), commonly referred to as prion diseases, are a group of rare, infectious and fatal neurodegenerative diseases in mammals. All prion diseases are thought to share a com...
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