PRION

作品数:175被引量:154H指数:5
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相关机构:中国农业大学中国科学院南加州大学厦门大学更多>>
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  • 期刊=Virologica Sinicax
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Tumor Necrosis Factor a Reduces SNAP29 Dependent Autolysosome Formation to Increase Prion Protein Level and Promote Tumor Cell Migration
《Virologica Sinica》2021年第3期458-475,共18页Huan Li Ren Wang Ze Yu Run Shi Jie Zhang Shanshan Gao Ming Shao Shuzhong Cui Zhenxing Gao Jiang Xu Man-Sun Sy Chaoyang Li 
supported by grants from the National Science Foundation of China (31670170 & 81560442);from MOST (2018YFA0507201);from the Natural Science Foundation of Guangdong Province (2017ZC0236)。
Tumor Necrosis Factor α(TNFα) is best known as a mediator of inflammation and immunity, and also plays important roles in tumor biology. However, the role of TNFα in tumor biology is complex and not completely unde...
关键词:Tumor necrosis factorα(TNFα) Prion protein Synaptosome associated protein 29(SNAP29) Autophagy Nuclear factor kappa B(NF-κB) Forkhead box P3(FOXP3) 
IP10, KC and M-CSF Are Remarkably Increased in the Brains from the Various Strains of Experimental Mice Infected with Different Scrapie Agents被引量:5
《Virologica Sinica》2020年第5期614-625,共12页Jia Chen Cao Chen Chao Hu Lian Liu Ying Xia Lin Wang Wei Yang Hai-Yan Wu Wei Zhou Kang Xiao Qi Shi Yuezhang Wu Zhi-Bao Chen Xiao-Ping Dong 
supported by the National Natural Science Foundation of China(81772197,81401670 and 81630062);the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences(2018RC330004);National Key R&D Program of China(2018YFC1200305Y);National Science and Technology Major Project of China(2018ZX10102001);SKLID Development Grant(2019SKLID401 and 2016SKLID603);the Natural Science Foundation of Heilongjiang Province(C2018044)
Activation of inflammatory cells and upregulations of a number of cytokines in the central nervous system(CNS)of patients with prion diseases are frequently observed.To evaluate the potential changes of some brain cyt...
关键词:PRION Cytokines Interferon gamma-induced protein 10(IP10) Keratinocyte chemoattractant(KC) Macrophage colony stimulating factor(M-CSF) 
Prion Protein Protects Cancer Cells against Endoplasmic Reticulum Stress Induced Apoptosis被引量:3
《Virologica Sinica》2019年第2期222-234,共13页Zhenxing Gao Min Peng Liang Chen Xiaowen Yang Huan Li Run Shi Guiru Wu Lili Cai Qibin Song Chaoyang Li 
supported by the Strategic Priority Research Program A of the Chinese Academy of Sciences (XDA12010309);the National Natural Science Foundation of China (31670170 and 31270209);the National Key R&D program of China (2018YFA0507201);the National Basic Research Priorities Program of China (2013CB911102) from the Ministry of Science and Technology of China
Unfolded protein response(UPR) is an adaptive reaction for cells to reduce endoplasmic reticulum(ER) stress. In many types of cancers, such as lung cancer and pancreatic cancer, cancer cells may harness ER stress to f...
关键词:Endoplasmic reticulum stress Brefeldin A (BFA) PRION protein (PrP)- GLYCOSYLATION Apoptosis 
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