We thank Drs Quan Chen, Mian Long, Chunyang Xiong and Zhihong Li for helpful discussions on the project. We thank Drs Peace Cheng, Nanping Wang, Xiaocheng Gu and Iain C Bruce for reading the manuscript and offering valuable comments. We also thank Dr Xiuqin Zhang and Ms Ning Hou for technical assistance. Jincai Luo is supported by grants from the National Basic Research Program of China (2012CB945100) and the National Natural Science Foundation of China (81170098 and 81070115). Yulong He is supported by the Priority Academic Program Development of Jiangsu Higher Education Institutions.
Regulated endothelial exocytosis of WeibelPalade bodies (WPBs), the first stage in leukocyte trafficking, plays a pivotal role in inflammation and injury. Acute mechanical stretch has been closely associated with va...
supported by the National Basic Research Program of China(Grant No. 2010CB833701);the National Natural Science Foundation of China(Grant Nos. 30870564 and 90913022);the CAS Project(Grant No.KSCX2-SW-224)
The molecular mechanisms by which dense core vesicles(DCVs) translocate,tether,dock and prime are poorly understood.In this study,Caenorhabditis elegans was used as a model organism to study the function of Rab protei...
This work was supported by the grants from the National Natural Science Foundation of China (30025023, 3000062, 30130230 and 30370647);the Major State Basic Research Program of China (G1999054000 and 2004CB720000);the Chinese Academy of Sciences Project (KSCX2-SW-224);the National High Technology Research and Development Program of China (2002AA214061).
α-Latrotoxin from the venom of black widow spider induces and augments neurotransmitter and hormone release by way of extracellular Ca^2+ influx and cellular signal transduction pathways. By using whole cell current...