EXOCYTOSIS

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Immuno-electron microscopy localizes Caenorhabditis elegans vitellogenins along the classic exocytosis route
《Life Metabolism》2024年第6期17-32,共16页Chao Zhai Nan Zhang Xi-Xia Li Xue-Ke Tan Fei Sun Meng-Qiu Dong 
funded by the National Natural Science Foundation of China(NSFC-ISF 32061143020 to M.Q.D.,31925026 to F.S.,and 31501160 to X.X.L.);the Ministry of Science and Technology of the People's Republic of China(institutional grants to NIBS,Beijing,a fund of the National High-Level Talents Special Support Program to M.Q.D.);Beijing Municipal Science and Technology Commission(institutional grants to NIBS,Beijing and a fund for cultivation and development of innovation base to M.Q.D.).
Vitellogenins(VITs)are the most abundant proteins in adult hermaphrodite Caenorhabditis elegans.VITs are synthesized in the intes-tine,secreted to the pseudocoelom,matured into yolk proteins,and finally deposited in o...
关键词：VITELLOGENIN YOLK immuno-EM EXOCYTOSIS Caenorhabditis elegans 
Ca^(2+) binding to the C_(2)E domain of otoferlin is required for hair cell exocytosis and hearing
《Protein & Cell》2024年第4期305-312,共8页Han Chen Mehar Monga Qinghua Fang Loujin Slitin Jakob Neef Shashank S.Chepurwar Regina Célia Mingroni Netto Karina Lezirovitz Alfredo Tabith,Jr. Fritz Benseler Nils Brose Kathrin Kusch Carolin Wichmann Nicola Strenzke Barbara Vona Julia Preobraschenski Tobias Moser 
supported by the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation),under Germany’s Excellence Strategy—EXC 2067/1-390729940(to T.M.,N.B.and J.P.),via the Collaborative Research Center 889(to N.S.,C.W.,J.P.,N.B.and T.M.),via DFG VO 2138/7‐1(to B.V.),and via the Leibniz Program(to T.M.);supported by Fondation Pour l’Audition(FPA RD-2020-10)to T.M.;Fundação de AmparoàPesquisa do Estado de São Paulo(CEPID 2013/08028-1)to R.C.M.N..
Dear Editor,Afferent synapses of cochlear inner hair cells(IHCs)employ a unique molecular machinery(see extended background in Supplementary Materials).Otoferlin is a key player in this machinery and its defects cause...
关键词：AUDITORY HAIR 
Synergistic regulation of fusion pore opening and dilation by SNARE and synaptotagmin-1
《Journal of Molecular Cell Biology》2024年第4期17-30,共14页Kaiju Li Kaiyu Li Jiaqi Fan Xing Zhang Chengyan Tao Yijuan Xiang Lele Cui Hao Li Minghan Li Yanjing Zhang Jia Geng Ying Lai 
supported by the National Natural Science Foundation of China(31900688 and 32170686 to Y.L.);Sichuan University West China Hospital(ZYYC21007 and Z2021JC007 to Y.L.);the National Key Research and Development Program of China(2022YFB3205600 to J.G.).
Fusion pore opening is a transient intermediate state of synaptic vesicle exocytosis,which is highly dynamic and precisely regulated by the soluble N-ethylmaleimide-sensitive factor attachment protein receptor(SNARE)c...
关键词：SNARE synaptotagmin-1 fusion pore vesicle exocytosis 
Recent progress and future directions of the research on nanoplastic-induced neurotoxicity
《Neural Regeneration Research》2024年第2期331-335,共5页Seung-Woo Han Jinhee Choi Kwon-Yul Ryu 
supported by the Basic Study and Interdisciplinary R&D Foundation of the University of Seoul(2019)grants,Nos.201910021035;202006251003(both to KYR and JC)。
Many types of plastic products,including polystyrene,have long been used in commercial and industrial applications.Microplastics and nanoplastics,plastic particles derived from these plastic products,are emerging as e...
关键词：AUTOPHAGY cellular stress CYTOTOXICITY ENDOCYTOSIS EXOCYTOSIS inflammation microplastics nanoplastics NEUROTOXICITY oxidative stress POLYSTYRENE 
Cellular journey of nanomaterials:Theories,trafficking,and kinetics Cellular journey of nanomaterials:Theories,trafficking,andkinetics
《Aggregate》2023年第6期11-26,共16页Xiangrui Wang Wen-Xiong Wang 
Hong Kong Research Grants Council,Grant/Award Numbers:11102321,C6014-20 W;Shenzhen Municipal Science and Technology Innovation Commission,Grant/Award Number:JCYJ20210324134000001。
Engineered nanomaterials(NMs)are increasingly fabricated in various fields involv-ing consumer goods,waste management,and biomedical applications such as drug delivery,diagnosis,and treatment of pathological condition...
关键词：cellular journey EXOCYTOSIS intracellulartrafficking kineticmodel 
Uptake and Intracellular Fate of Fluorophore Labeled Metal−Organic-Framework(MOF)Nanoparticles
《Environment & Health》2023年第4期270-277,共8页Ziyao Liu Andreas Zimpel Ulrich Lächelt Maria Pozzi Marta Gallego Gonzalez Indranath Chakraborty Stefan Wuttke Neus Feliu Wolfgang J.Parak 
supported by the project HeatNMof(European Union’s Horizon 2020 program).N.F.was funded by Fraunhofer Attract(Fraunhofer-Gesellschaft).Z.L.was supported by China Scholarship Council(CSC).
The uptake and the fate of Zr-based metal−organic-framework nanoparticles labeled with organic fluorophores in HeLa cells has been monitored with fluorescence detection and elemental analysis.The nanoparticles have be...
关键词：nanoparticle endocytosis EXOCYTOSIS proliferation fate of nanoparticles intracellular degradation metal organic framework nanoparticles 
Exocytosis,endocytosis and recycling of secretory vesicles in neuroendocrine cells,and its regulation by cortical actin
《BIOCELL》2022年第8期1867-1873,共7页ANA M.CÁRDENAS I.GALLO FERNANDO D.MARENGO 
This work was supported by the Grants PICT 2764-2016,PICT 02849-2018 and PICT 02041-2019 from the Agencia Nacional de Promoción de la Investigación,el Desarrollo Tecnológico y la Innovación(Argentina);ICN09_022 from ICM-ANID(Chile).
The cortical actin network is a mesh of filaments distributed beneath the plasmalemma that dynamically reacts in response to stimuli.This dynamic network of cortical filaments,together with motor myosin partners,adjus...
关键词：Cortical actin Neuroendocrine cell Chromaffin cell EXOCYTOSIS ENDOCYTOSIS 
The tip of the iceberg:ROP2 directly interacts with SYP121 to regulate root-hair polarization,elongation,and exocytosis
《Molecular Plant》2022年第7期1084-1086,共3页Martiniano M.Ricardi Jose M.Estevez 
supported by grants from ANPCyT PICT2019-0015,by ANID-Programa lniciativa Cientffica Milenio NCN2021_010;Fondo Nacional de Desarrollo Cientffico y Tecnol6gico(1200010)to J.M.E.
Root hairs(RHs)grow in a polar manner as cylindrical protrusions from the root epidermis.They significantly expand the root volume in the rhizosphere to search for water and nutrients,anchor the plant,and promote inte...
关键词：TIP POLARIZATION cylindrical 
Arabidopsis SYP121 acts as an ROP2 effector in the regulation of root hair tip growth被引量：1
《Molecular Plant》2022年第6期1008-1023,共16页Xiankui Cui Shuwei Wang Yaohui Huang Xuening Ding Zirong Wang Lidan Zheng Yujing Bi Fanghui Ge Lei Zhu Ming Yuan Shaul Yalovsky Ying Fu 
supported by the National Natural Science Foundation of China(grant no.32061143018 and 91854119 to Y.F.);a China Postdoctoral Science Foundationgrant(2016M591291 to S.W.).Noconflict of interest declared.
Tip growth is an extreme form of polarized cell expansion that occurs in all eukaryotic kingdoms to generate highly elongated tubular cells with specialized functions, including fungal hyphae, animal neurons, plant po...
关键词：ROP GTPase SYP121 SNARE protein EXOCYTOSIS root hair tip growth 
Plant exocytosis: Weaving distinct pathways to the plant plasma membrane
《Molecular Plant》2022年第3期382-384,共3页Erik Nielsen 
During plant growth and development newly synthesized proteins and other cargo molecules must be selectively targeted to a variety of cellular compartments.Perhaps the most important targeting involves the trafficking...
关键词：neighboring PROCESSED complex 
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