ANTI-IGE

作品数：5被引量：12H指数：1
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相关领域：医药卫生更多>>
相关作者：张涛代云见何勇智丛聪张勇侠更多>>
相关机构：锦州医科大学成都生物制品研究所有限责任公司沈阳军区总医院清华大学更多>>
相关期刊：《中国生物工程杂志》《Cellular & Molecular Immunology》《Acta Pharmacologica Sinica》《Journal of Biomedical Research》更多>>
相关基金：“重大新药创制”科技重大专项北京市自然科学基金国家自然科学基金更多>>
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Current State of Monoclonal Antibody Therapy for Allergic Diseases
《Engineering》2021年第11期1552-1556,共5页Yan Chen Wei Wang Huihui Yuan Yan Li Zhe Lv Ye Cui Jie Liu Sun Ying 
This work was supported by grants from the National Natural Science Foundation of China(81471594,81770049,and 81700026);the Natural Science Foundation of Beijing Municipality(7192023).
Allergic disease is one of the most common chronic diseases,which can affect both children and adults,be often caused by allergen-induced unfavorable immune responses,and initiate various symptoms in different organs,...
关键词：Allergic disease Monoclonal antibody ANTI-IGE CYTOKINES Clinical trials 
Anti-IgE IgG autoantibodies isolated from therapeutic normal IgG intravenous immunoglobulin induce basophil activation
《Cellular & Molecular Immunology》2020年第4期426-429,共4页Caroline Galeotti Anupama Karnam Jordan D.Dimitrov Alain Chevailler Srini V.Kaveri Jagadeesh Bayry 
supported by the Institut National de la Santéet de la Recherche Médicale(INSERM);Sorbonne Université,UniversitéParis Descartes,ANR-19-CE17-0021(BASIN);CSL Behring,Switzerland.C.G.and A.K.were the recipients of fellowships from La Fondation pour la Recherche Médicale(FDM20150633674 and FDT201805005552,respectively),France。
Basophils are rare granulocytes.Despite representing only~0.5%of all leukocytes,basophils have several important physiological functions.1,2 Although basophils lack the classic features of professional antigen-present...
关键词：activation ATTEMPTED IgE 
Anti-IgE单链抗体纯化工艺研究及活性鉴定被引量：1
《中国生物工程杂志》2015年第12期51-57,共7页代云见 张勇侠 何勇智 丛聪 张涛 王明蓉 
国家"十二五""重大新药创制"科技重大专项资助项目(2011ZX09506-005)
目的:建立anti-IgE单链抗体纯化工艺并对其活性进行鉴定。方法:根据protein L亲和层析填料和Ni亲和层析填料的特点分析,经初筛后选用protein L填料作为第一步初纯化填料,Ni亲和层析填料作为第二步精细纯化填料。通过对这两种纯化方式的...
关键词：anti-IgE单链抗体 proteinL亲和层析 Ni亲和层析 哮喘 
Omalizumab(Anti-IgE)在重度气喘的角色～过敏体质的捕手
《台灣氣喘衛教學會會刊》郭聰懷 
创世纪的新药，Anti-IgE在治疗气喘的角色
《台灣氣喘衛教學會會刊》林慶雄 
Activation of human tonsil and skin mast cells by agonists of proteinase activated receptor-2被引量：11
《Acta Pharmacologica Sinica》2005年第5期568-574,共7页Shao-hengHE HuaXIE Yi-lingFU 
Project supported by the Planned Science and Technology Project of GuangdongProvince,China,№ 2003B31502;the Li Ka Shing Foundation,Hong Kong,China,№ C0200001
Aim:To investigate the effects of the agonists of proteinase activated receptor (PAR)-2,and histamine on degranulation of human mast cells.Methods:Human mast cells were enzymatically dispersed from tonsil and skin tis...
关键词：TRYPTASE histamine mast cells proteinase activated receptor-2 ANTI-IGE TONSIL SKIN 
Anti-IgE Induced 5-Hydroxy Tryptamine Release from Rat Peritoneal Mast Cells
《The Journal of Biomedical Research》1996年第1期30-31,47,共3页黄钦田 徐桦 郑茂锭 
Immediatehypersensitivityisrelatedwithcroslinkingofcel-boundIgEonthesurfaceofmastcelsandbasophils.Ratswereimmunizedwithovalbuminandtheperitonealmastcelswerecolectedfromimmunizedratsandchalengedwithrabitanti-ratIgEseru...
关键词：ANTI-IGE MEDIATOR mastcel SEROTONIN 
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