TRYPTASE

作品数:33被引量:92H指数:5
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相关领域:医药卫生更多>>
相关作者:李艳金晶纯黄世光李娟许慈燕更多>>
相关机构:汕头大学中国医科大学附属第一医院暨南大学中山大学更多>>
相关期刊:《World Journal of Clinical Pediatrics》《免疫学杂志》《海南医学》《Food Science and Human Wellness》更多>>
相关基金:国家自然科学基金中国科学院科研项目广东省社会发展领域科技计划项目国家重点基础研究发展计划更多>>
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Effects of acupuncture on serotonin,histamine,substance P,and tryptase levels at sensitized points in model rats with knee osteoarthritis
《Journal of Traditional Chinese Medical Sciences》2024年第4期500-512,共13页Jiayi Yang Zidong Wang Jing Jiang Huiling Tian Shun Wang Yizhi Liu Zumao Cao Changqing Joseph Yang Zhigang Li 
supported by the National Natural Science Foundation of China(81590952);the“Jiebang Guashuai”Project of the Beijing University of Chinese Medicine(2022-JYB-JBZR-024).
Objective:To elucidate the differences in manual acupuncture effectiveness at sensitized points by investigating the mechanisms of local skin action at different sensitization points in rats with knee osteoarthritis(K...
关键词:Knee osteoarthritis ACUPUNCTURE Acupoint sensitization Mast cells SEROTONIN HISTAMINE Substance P TRYPTASE 
Treatment refractory mast cell leukemia with dominant gastrointestinal manifestation and concomitant skin symptoms:A case report
《World Journal of Clinical Cases》2024年第20期4317-4324,共8页Maciej Tomasz Wysocki Maciej Gonciarz Bartosz Puła 
BACKGROUND Mast cell leukemia(MCL),a subtype of systemic mastocytosis(SM),is an extremely rare clinical entity characterized by a very poor prognosis.Chemotherapy,tyrosine kinase inhibitors,and allogeneic hematopoieti...
关键词:MASTOCYTOSIS Systemic mastocytosis Mast cell leukemia TRYPTASE Case report 
Close relationship between mediators of inflammation and pancreatic cancer:Our experience被引量:1
《World Journal of Gastroenterology》2024年第23期2927-2930,共4页Francesca Vescio Michele Ammendola Giuseppe Currò Silvia Curcio 
In this editorial,we focus specifically on the mechanisms by which pancreatic inflammation affects pancreatic cancer.Cancer of the pancreas remains one of the deadliest cancer types.The highest incidence and mortality...
关键词:Mast cells C-Kit receptor TRYPTASE Angiogenesis Microvascular density Endothelial area Pancreatic tumor tissue Adjacent normal tissue 
Lactobacillus plantarum AR495 improves stress-induced irritable bowel syndrome in rats by targeting gut microbiota and Mast cell-PAR2-TRPV1 signaling pathway
《Food Science and Human Wellness》2024年第2期698-708,共11页Hongyun Zhang Guangqiang Wang Zhiqiang Xiong Zhuan Liao Yangyan Qian Xin Song Li Sui Lianzhong Ai Yongjun Xia 
supported by the shanghai agriculture applied technology development program(2019-02-08-00-07-F01152);the national science fund for distinguished young scholars(32025029);the shanghai engineering research center of food microbiology program(19DZ2281100);the national key R&D program of china(2018YFC1604305)。
Probiotics have great potential in regulating intestinal pain.In this study,the effects of Lactobacillus plantarum AR495 on the visceral sensitivity and gut microbiota of irritable bowel syndrome(IBS)rats were studied...
关键词:Lactobacillus plantarum Irritable bowel syndrome Visceral sensitivity Dorsal root ganglia TRYPTASE MICROBIOTA 
通心络辅助尼可地尔对心肌梗死冠脉微循环障碍患者血清Tryptase、Copeptin表达的影响被引量:2
《中国老年学杂志》2024年第6期1285-1287,共3页姜倩倩 冯泽瑞 崔金珍 常以芳 
山东省医药卫生科技发展计划项目(2015WS0404);山东省自然科学基金项目(202115268)。
目的 研究通心络辅助尼可地尔治疗心肌梗死冠脉微循环障碍(MI-CMVD)对类胰蛋白酶(Tryptase)、和肽素(Copeptin)表达的影响。方法 212例MI-CMVD患者随机分为对照组和观察组各106例。对照组予以尼可地尔进行治疗,观察组予以尼可地尔+通心...
关键词:通心络 尼可地尔 心肌梗死冠脉微循环 血清类胰蛋白酶(Tryptase) 和肽素(Copeptin) 
Mast cell activation syndrome:An up-to-date review of literature
《World Journal of Clinical Pediatrics》2024年第2期104-113,共10页ÖnerÖzdemir Gökçe Kasımoğlu Ayşegül Bak Hüseyin Sütlüoğlu Süreyya Savaşan 
Mast cells are a subtype of white blood cells and are involved in the immune system.These cells contain many chemical substances called mediators,which are involved in the allergic response.The fact that mast cells pl...
关键词:Mast cell Mast cell activation syndrome TRYPTASE HISTAMINE 
腹部推拿调控Tryptase-PAR2-PKCε通路防治IBS-D内脏痛的机制研究被引量:1
《天津中医药》2023年第1期75-81,共7页李华南 王毓岩 张小凡 张玮 马菲 董桦 王金贵 
国家自然科学基金项目(81873394);国家中医药管理局中医药传承与创新“百千万”人才工程(岐黄工程)岐黄学者(国中医药人教函〔2021〕203号);国家区域中医(推拿)诊疗中心项目;天津市131优秀人才培养项目。
[目的]验证腹部推拿防治腹泻型肠易激综合征(IBS-D)模型大鼠内脏高敏感的效果,阐明其作用途径与机制。[方法]40只SD雄性大鼠,随机分为空白组、模型组、腹部推拿组、西药组,每组10只。采用母婴分离结合慢性应激法制备IBS-D大鼠模型。应...
关键词:腹部推拿 腹泻型肠易激综合征 内脏高敏感 TRYPTASE PAR2 PKCΕ 
Glutamate triggers the expression of functional ionotropic and metabotropic glutamate receptors in mast cells被引量:2
《Cellular & Molecular Immunology》2021年第10期2383-2392,共10页Md Abdul Alim Mirjana Grujic Paul W.Ackerman Per Kristiansson Pernilla Eliasson Magnus Peterson Gunnar Pejler 
This study was funded by grants from AFA Forsakring(M.P.).
Mast cells are emerging as players in the communication between peripheral nerve endings and cells of the immune system.However,it is not clear the mechanism by which mast cells communicate with peripheral nerves.We p...
关键词:GLUTAMATE Glutamate receptors Mast cells NMDA receptors TRYPTASE 
Early development and functional properties of tryptase/chymase double-positive mast cells from human pluripotent stem cells被引量:1
《Journal of Molecular Cell Biology》2021年第2期104-115,共12页Guohui Bian Yanzheng Gu Changlu Xu Wenyu Yang Xu Pan Yijin Chen Mowen Lai Ya Zhou Yong Dong Bin Mao Qiongxiu Zhou Bo Chen Tatsutoshi Nakathata Lihong Shi Min Wu Yonggang Zhang Feng Ma 
This work was supported by the National Basic Research Program(973 Program;2015CB96A902);the National Natural Science Foundation of China(H81170466 and H81370597);and the CAMS Initiatives for Innovative Medicine(2016-I2M-1-018)awarded to F.M.;the CAMS Initiatives for Innovative Medicine(2017-12M-2005);the Union Youth Fund of Chinese Academy of Medical Sciences(81572089)to G.B.;and the National Nature Science Foundation of China Youth Fund(81700107)to B.M.
Mast cells (MCs) play a pivotal role in the hypersensitivity reaction by regulating the innate and adaptive immune responses. Humans have two types of MCs. The first type, termed MCTC, is found in the skin and other c...
关键词:mast cells human pluripotent stem cells(hPSCs) development TRYPTASE CHYMASE 
通过MC-Tryptase-PAR-2-FLS途径探讨资木瓜总苷对K/B×N小鼠血清转移性关节炎的治疗作用被引量:1
《中国免疫学杂志》2021年第4期395-399,409,共6页周婷婷 陈先勇 陈桂婷 曹楠 李世刚(指导) 
国家自然科学基金项目(81673665,81274166);湖北省卫生健康委员会联合基金重点项目(WJ2019H531)
目的:研究资木瓜总苷(TSCS)通过MC-Tryptase-PAR-2-FLS途径对K/B×N小鼠血清转移性关节炎的治疗作用。方法:小鼠随机分为6组:C57BL/6小鼠分别注射C57BL/6小鼠血清、K/B×N小鼠血清作为正常对照组和模型组,KitW-4Bao小鼠注射K/B×N小鼠...
关键词:肥大细胞 类胰蛋白酶 PAR-2 成纤维样滑膜细胞 资木瓜总苷 K/B×N小鼠血清转移性关节炎模型 
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