SNP mutations in the HOXB13 gene associated with prostate cancer were determined in Moroccans prostate cancer patients (PCa). All PCa SNP mutations were new and belong to the SNP point-mutations located on the stop co...
supported by the Max Planck Society and Harvard Medical School.
The Y‑chromosome has been widely used in ancestry inference based on its region‑specific haplogroup distributions.However,there is always a debate on how informative such a single marker is for inferring an individual...
supported by the National Excellent Youth Science Foundation of China(No.31222030);the National Natural Science Foundation of China(No.91131002);the Shanghai Rising-Star Program(No.12QA1400300);the China Ministry of Education Scientific Research Major Project(Nos. 311016 and 113022A);the MOE University Doctoral Research Supervisor's Funds(No.20120071110021);the Shanghai Professional Development Funding(No.2010001)
The paternally inherited Y chromosome has been widely used in forensics for personal identification, in anthropology and population genetics to understand origin and migration of human populations, and also in medical...
This work was supported by the grant 81322017 from the National Natural Science Foundation of China, grant NCET-13-0736 from Program for New Century Excellent Talents in University, National Key Clinical Specialty Discipline Construction Program and Key Clinical Specialty Discipline Construction Program of Fujian.
Background: Mitochondrial dysflmction is linked to the pathogenesis of Parkinson's disease (PD). However, the precise role of mitochondrial DNA (mtDNA) variations is obscure. On the other hand, mtDNA haplogroups...
The relationships between five classes of Japanese people (i.e., 96 centenarians, 96 Alzheimer's disease (AD) patients, 96 Parkinson's disease (PD) patients, 96 type 2 diabetic (T2D) patients, and 96 healthy ...
Aim: To evaluate for the first time the frequency of Y chromosome microdeletions and the occurrence of the partial deletions of AZFc region in Moroccan men, and to discuss the clinical significance of AZF deletions. ...