Point mutations in SPG4,the gene encoding spastin,are a frequent cause of hereditary spastic paraplegia(HSP).In some complex HSP cases,there is cognitive impairment.Dynamic trafficking of AMPA receptors into and out o...
This study was supported by grants from the National Natural Science Foundation of China (No. 81000778, 81370050, and 81172549) and the Scientific Research and Innovation of Shanghai Municipal Education Commission (No. 11YZ46).
Background Recent studies on bone have shown an endocrine role of the skeleton,which could be impaired in various human diseases,including osteoporosis,obesity,and diabetes-associated bone diseases.As a sensor and reg...
Project supported by the National Natural Science Foundation of China (Nos. 20875093 and 90813021) and the Pilot Project of Knowledge Innovation Program of the Chinese Academy of Sciences (No. KJCX2-SW-w29).
So far it is unclear whether the release of oxygen-evolving complex (OEC) subunits including PsbO, PsbP, and PsbQ proteins is affected by the phosphorylation of photosystem II (PSII) membranes under light stress. ...
The efficient translation of most eukaryotic mRNAs requires an interaction between the 5' m7GTP cap structure of mRNA and eIF-4F which is composed of 25-(eIF 4E),46-(eIF-4A), and 220-kDa (p220) subunits. eIF-4E binds ...