Veratridine is a lipid-soluble neurotoxin derived from plants in the family Liliaceae. it has been broadly investigated for its action as a sodium channel agonist However, the effects of veratridine on subtypes of sod...
This work was supported by the National Natural Science Foundation of China (No 81072637). We also thank Ms Na LUO of the University of Hong Kong for her editorial assistance with this paper.
Aim: The augmentation of late sodium current (/Na.L) not only causes intracellular Na^+ accumulation, which results in intracellular Ca^2+ overload via the reverse mode of the Na^+/Ca^2+ exchange current (reve...
Poneratoxin (PoTX) is an insect neuropeptide isolated from ant venom. It was previously demonstrated that administration of synthetic PoTX into the lateral brain ventricle (icv) induced in rats significant antinoc...