BENFOTIAMINE

作品数：6被引量：15H指数：2
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Long-Term Cognitive Improvement After Benfotiamine Administration in Patients with Alzheimer＇s Disease被引量：11
《Neuroscience Bulletin》2016年第6期591-596,共6页Xiaoli Pan Zhichun Chen Guoqiang Fei Shumei Pan Weiqi Bao Shuhua Ren Yihui Guan Chunjiu Zhong 
supported by the Key Fund for Developing New Drugs from the Ministry of Science and Technology of China(2014ZX09101005-005);the National Natural Science Foundation of China(81071019);the National Key Basic Research Program of China(2011CBA00400);the Natural Science Foundation of Shanghai Municipality,China(13JC1401500);the Fund for Medical Emerging Cutting-Edge Technology in Shanghai of China (SHDC12012114)
Abstract To date, we still lack disease-modifying thera- pies for Alzheimer＇s disease （AD）. Here, we report that long-term administration of benfotiamine improved the cognitive ability of patients with AD. Five pat...
关键词：Alzheimer＇s disease. Therapy. Benfotiamine PiB-PET Amyloid deposition 
Benfotiamine prevents increased β-amyloid production in HEK cells induced by high glucose
《Neuroscience Bulletin》2012年第5期561-566,共6页Xiao-Jing Sun Lei Zhao Na Zhao Xiao-Li Pan Guo-Qiang Fei Li-Rong Jin Chun-Jiu Zhong 
supported by grants from the National Natural Science Foundation of China(81071019);the International Cooperation Foundation of Shanghai Municipality, China (10430709600);the Outstanding Academic Leaders Foundation in Shanghai, China(11XD1401500)
Objective To determine whether high glucose enhances β-amyloid （Aβ） production in HEK293 Swedish mutant （APPsw） cells with Aβ precursor protein （APP） overexpression, and whether under this condition benfotiam...
关键词：Alzheimer’s disease Β-AMYLOID high glucose BENFOTIAMINE glycogen synthase kinase 
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