Introduction: There are extensive people exposures to paraquat (PQ) herbicide resulting in human health hazards. Aim of the Work: To compare the beneficial neuroprotective effects of ...
supported by Fundacao de Amparo a pesquisa de Minas Gerais(FAPEMIG)[grant number:APQ-00039-15];Conselho Nacional de Desenvolvimento Científico e Tecnologico(CNPq)[grant number:423171/2016-0]
Objective: This study aimed to evaluate the influence of oral supplementation with benfotiamine on oxidative stress in the liver, heart and muscles of endurance-trained mice.Methods: Twenty-five male BALB/c mice were ...
supported by the Key Fund for Developing New Drugs from the Ministry of Science and Technology of China(2014ZX09101005-005);the National Natural Science Foundation of China(81071019);the National Key Basic Research Program of China(2011CBA00400);the Natural Science Foundation of Shanghai Municipality,China(13JC1401500);the Fund for Medical Emerging Cutting-Edge Technology in Shanghai of China (SHDC12012114)
Abstract To date, we still lack disease-modifying thera- pies for Alzheimer's disease (AD). Here, we report that long-term administration of benfotiamine improved the cognitive ability of patients with AD. Five pat...
Background: Peripheral neuropathy is a commonly encountered troublesome condition which is often disabling & worsens when left untreated. Traditional neuropathic pain medications primarily provide symptomatic relief;h...
Supported by The Grant from the Ministry of Health of Czech Republic,No.NT13198
Growing prevalence of diabetes(type 2 as well as type 1) and its related morbidity due to vascular complications creates a large burden on medical care worldwide. Understanding the molecular pathogenesis of chronic mi...
supported by grants from the National Natural Science Foundation of China(81071019);the International Cooperation Foundation of Shanghai Municipality, China (10430709600);the Outstanding Academic Leaders Foundation in Shanghai, China(11XD1401500)
Objective To determine whether high glucose enhances β-amyloid (Aβ) production in HEK293 Swedish mutant (APPsw) cells with Aβ precursor protein (APP) overexpression, and whether under this condition benfotiam...