This work was supported by"the Joint Fund for New Medicine of USTC"(Grant No.YD9100002040);the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB0490000);the National Key Research and Development Program of China(Grant No.2022YFC2304102).
The ongoing pandemic caused by mpox virus(MPxV)has become an international public health emergency that poses a significant threat to global health.The vaccinia virus Tiantan strain(VTT)was used to vaccinate against s...