SUSCEPTIBILITY

作品数：947被引量：1994H指数：16
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相关机构：南京医科大学江苏省人民医院中南大学复旦大学更多>>
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Exogenous ketogenic supplements can mitigate the susceptibility to Alzheimer's disease induced by chronic sleep deprivation:emerging role of Sirt1 in ferroptosis
《Food Science and Human Wellness》2025年第3期1034-1044,共11页Yueqi Yang Xueyan Wang Lu Chen Ning Zhang Shilei Ji Zhengping Wang Jun Han Yuming Wang Min Wen 
supported by Natural Science Foundation of Shandong province(ZR2021QH022,ZR2021QB198);National Natural Science Foundation of China(82001286);the Open Project of Liaocheng University Animal Husbandry Discipline(319462207-24)。
Emerging evidence supports that sleep disorders are the main risk factor for sporadic Alzheimer's disease(AD),and iron dysregulation may be the link between them.Our previous studies have confirmed that ketogenic diet...
关键词：Sleep loss Alzheimer’s disease Ferroptosis Mitochondrial dysfunction Silent information regulator 1 
Dip2a regulates stress susceptibility in the basolateral amygdala
《Neural Regeneration Research》2025年第6期1735-1748,共14页Jing Li Zixuan He Weitai Chai Meng Tian Huali Yu Xiaoxiao He Xiaojuan Zhu 
supported by the STI 2030—Major Projects 2021ZD0204000,No.2021ZD0204003 (to XZ);the National Natural Science Foundation of China,Nos.32170973 (to XZ),32071018 (to ZH)。
Dysregulation of neurotransmitter metabolism in the central nervous system contributes to mood disorders such as depression, anxiety, and post–traumatic stress disorder. Monoamines and amino acids are important types...
关键词：5-HYDROXYTRYPTAMINE acute restraint stress basolateral amygdala CaMKII neurons DIP2A metabolomics NEUROTRANSMITTERS principal component analysis stress susceptibility TRYPTOPHAN 
Predicting anti-cancer drug sensitivity through WRE-XGBoost algorithm with weighted feature selection
《Genes & Diseases》2025年第2期15-17,共3页Yiyao Jiang Ming Chen Zhongmin Xiong Yufang Qin 
supported in part by the Shanghai Science and Technology Innovation Action Planning (No.20dz1203800 to M.C.);the Research and Development Planning in Key Areas of Guangdong Province,China (No.2021 B0202070001 to M.C.);the National Natural Sci-ence Foundation of China (No.61702325 to Y.Q.).
Accurate prediction of drug susceptibility is one of themost important steps in personalized medicine.Applications of machine learning to pharmacogenomic data for sensitivity prediction can help study the mechanism of...
关键词：STEPS SUSCEPTIBILITY ALGORITHM 
Superconductivity in titanium probed by AC magnetic susceptibility to 120 GPa
《Chinese Physics B》2025年第4期575-577,共3页Jing Song Hongyu Liu Xiancheng Wang Changqing Jin 
Project supported by the National Key Research and Development Program of China(Grant No.2023YFA1406000);the National Natural Science Foundation of China(Grant No.12204514).
We used a highly sensitive AC magnetic susceptibility technique to probe superconductivity in elemental titanium(Ti)under extreme pressures to 120 GPa in a diamond anvil cell(DAC).The measurements reveal that the crit...
关键词：SUPERCONDUCTIVITY high pressure SUSCEPTIBILITY 
Flood frequency analysis and susceptibility zonation of the Haora River Basin,Northeast India
《River》2025年第1期116-133,共18页Asif Iqbal Shah Kirtica Das Nibedita Das Pan 
Flooding remains one of the most destructive natural disasters,posing significant risks to both human lives and infrastructure.In India,where a large area is susceptible to flood hazards,the importance of accurate flo...
关键词：analytic hierarchy process disaster management flood frequency analysis flood Risk flood susceptibility North East India VULNERABILITY 
Deciphering decision-making mechanisms for the susceptibility of different slope geohazards:A case study on a SMOTE-RF-SHAP hybrid model
《Journal of Rock Mechanics and Geotechnical Engineering》2025年第3期1612-1630,共19页Junhao Huang Haijia Wen Jiwei Hu Bo Liu Xinzhi Zhou Mingyong Liao 
the National Key Research and Development Program of China(Grant No.2023YFC3007203).
Different slope geohazards have different causal mechanisms.This study aims to propose a method to investigate the decision-making mechanisms for the susceptibility of different slope geohazards.The study includes a g...
关键词：Random forest Machine learning SMOTE Slope geohazards 
Ventral Hippocampal CA1 GADD45B Regulates Susceptibility to Social Stress by Influencing NMDA Receptor‑Mediated Synaptic Plasticity
《Neuroscience Bulletin》2025年第3期406-420,共15页Mengbing Huang Jian Bao Xiaoqing Tao Yifan Niu Kaiwei Li Ji Wang Xiaokang Gong Rong Yang Yuran Gui Hongyan Zhou Yiyuan Xia Youhua Yang Binlian Sun Wei Liu Xiji Shu 
supported by the National Natural Science Foundation of China(82201667,82371195,and 82304474);the Research Fund of Jianghan University(2023JCYJ15).
Growth arrest DNA damage-inducible protein 45β(GADD45B)has been reported to be a regulatory factor for active DNA demethylation and is implicated in the modulation of synaptic plasticity and chronic stress-related ps...
关键词：Chronic stress Ventral hippocampal CA1 GADD45B NMDA receptor Synaptic plasticity 
VTA is the Key to Pain Resilience in Empathic Behavior
《Neuroscience Bulletin》2025年第2期349-351,共3页Xue-Qing Wu Yi-La Ding Yu Du Zhong Chen Bei Tan 
supported by grants from the National Natural Science Foundation of China(82304459).
Pain has been traditionally understood as a complex phenomenon involving various dimensions,including physical,sensory,cognitive,and emotional aspects,resulting in unpleasant sensations and affective responses.Individ...
关键词：nociceptive stimuli pathological mechanisms empathic behavior pain resilience neural mechanisms pain susceptibility 
Ecological immunology:do sexual attraction and immunity trade-off through a desaturase?
《Insect Science》2025年第1期290-300,共11页Ke Gao Wout van der Heide Daphne Muijderman Sarah Nichols Carmen Karwal Peter Kuperus Astrid T.Groot 
funded in part by the National Science Foundation(NSF)grant(IOS-1456973);the Netherlands organization for Scientific Research,the Netherlands(NWO-ALW,822.01.012 and ALWOP 2015.075);the China Scholarship Council(CSC)scholarship(no.201506300162);the University of Amsterdam.
Given the limited availability of resources in nature,sexual attractiveness may trade off with immunocompetence,as the immunocompetence handicap hypothesis(ICHH)posits.In invertebrates,a direct link between trade-offs...
关键词：Chloridea virescens delta-11-desaturase ICHH parasite susceptibility sex pheromone 
Improving neuroblastoma risk prediction through a polygenic risk score derived from genome-wide association study-identified loci
《Chinese Journal of Cancer Research》2025年第1期1-11,共11页Wenli Zhang Jinhong Zhu Mengzhen Zhang Jiaming Chang Jiabin Liu Liping Chen Xinxin Zhang Haiyan Wu Chunlei Zhou Jing He 
supported by grants from the National Natural Science Foundation of China(No.82173593,32300473);Guangzhou Science and Technology Project(No.2025A04J4537,2025A04J4696);Guangdong Basic and Applied Basic Research Foundation(No.2023A1515220053);Postdoctoral Science Foundation of Jiangsu Province(No.2021K524C).
Objective:Neuroblastoma is the most common extracranial solid tumor in children and has complex genetic underpinnings.Previous genome-wide association studies(GWASs)have identified many loci associated with neuroblast...
关键词：GWAS POLYMORPHISM NEUROBLASTOMA SUSCEPTIBILITY polygenic risk score 
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