R-LOOPS

作品数：5被引量：6H指数：2
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相关作者：王文杰更多>>
相关机构：清华大学华中科技大学中南大学台湾大学更多>>
相关期刊：《Molecular Plant》《中国科学：生命科学》《Journal of Integrative Plant Biology》《Journal of Genetics and Genomics》更多>>
相关基金：国家自然科学基金北京市自然科学基金更多>>
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ILF3 safeguards telomeres from aberrant homologous recombination as a telomeric R-loop reader
《Protein & Cell》2024年第7期493-511,共19页Chuanle Wang Yan Huang Yue Yang Ruofei Li Yingying Li Hongxin Qiu Jiali Wu Guang Shi Wenbin Ma Zhou Songyang 
National Natural Science Foundation(Grant Nos.82271598,81871109,82071587,31930058,32330023 and 32170757);National Key Research and Development Program of China(2018YFA0107003);Guang Dong Basic and Applied Basic Research Foundation(2020A1515010462).
Telomeres are specialized structures at the ends of linear chromosomes that protect genome stability.The telomeric repeat-containing RNA(TERRA)that is transcribed from subtelomeric regions can invade into double-stran...
关键词：ILF3 RNA:DNA hybrids telomeric R-loops homologous recombination telomeric DNA damage responses 
三链染色质结构R-loop的研究进展:从检测方法到生物学功能被引量：1
《中国科学：生命科学》2023年第3期289-303,共15页周劲聪 王文杰 孙前文 
国家自然科学基金(批准号:32170321,31822028,91940306)资助。
R-loop是由一条单链DNA和另一条RNA∶DNA杂合链组成的三链染色质结构,在众多生物体中发挥着重要的生物学功能.生物体内有众多调控因子通过调节R-loop的稳态来影响各水平的基因组调控事件,如转录、复制、DNA损伤及修复等.近年来,随着R-l...
关键词：RNA:DNA杂合链 R-LOOPS 基因组调控 
A hypothetical model of trans-acting R-loops-mediated promoter-enhancer interactions by Alu elements被引量：1
《Journal of Genetics and Genomics》2021年第11期1007-1019,共13页Xue Bai Feifei Li Zhihua Zhang 
the National Natural Science Foundation of China of China(91940304,31871331,31671342);Beijing Natural Science Foundation(Z200021);Special Investigation on Science and Technology Basic Resources of MOST,China(2019FY100102);the National Key R&D Program of China(2018YFC2000400);the Beijing Advanced Discipline Fund(115200S001)。
Enhancers modulate gene expression by interacting with promoters.Models of enhancer-promoter interactions(EPIs)in the literature involve the activity of many components,including transcription factors and nucleic acid...
关键词：ALU Enhancer-promoter interaction eRNA R-loop 
Genome-wide profiling of circular RNAs,alternative splicing,and R-loops in stem-differentiating xylem of Populus trichocarpa被引量：3
《Journal of Integrative Plant Biology》2021年第7期1294-1308,共15页Xuqing Liu Yubang Gao Jiakai Liao Miao Miao Kai Chen Feihu Xi Wentao Wei Huihui Wang Yongsheng Wang XiXu Anireddy S.N.Reddy Lianfeng Gu 
supported by the National Key R&D Programof China(2016YFD0600106).
Circular RNAs(circRNAs)are a recently dis-covered type of non‐coding RNA derived from pre‐mRNAs.R‐loops consist of a DNA:RNA hybrid andthe associated single‐stranded DNA.InArabi-dopsis thaliana,circRNA:DNA R‐loop...
关键词：alternative splicing circular RNA R‐loop Populustrichocarpa stem‐differentiating xylem 
DNA Topoisomerase 1 Prevents R-loop Accumulation to Modulate Auxin-Regulated Root Development in Rice被引量：2
《Molecular Plant》2017年第6期821-833,共13页Sarfraz Shafiq Chunli Chen Jing Yang Lingling Cheng Fei Ma Emilie Widemann Qianwen Sun 
This work was supported by the National Natural Science Foundation of China （30900070, to C.C.）, Tsinghua University initiative Scientific Research Program, Tsinghua-Peking Joint Center for Life Sciences, and 1000 Young Talent Program of China （to The Sun Lab）. S.S. and E.W. were supported by postdoctoral fellowships from Tsinghua-Peking Joint Center for Life Sciences.
R-loop structures （RNA：DNA hybrids） have important functions in many biological processes, including transcriptional regulation and genome instability among diverse organisms. DNA topoisomerase 1 （TOP1）, an essen...
关键词：R-LOOPS DNA TOP1 auxin signaling root development 
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