supported by the Chinese Academy of Sciences (Grant Nos. E4V4061 and E2VK311);supported by the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences (Grant No. 2021-I2M-1-037);supported by the National Natural Science Foundation of China (Grant Nos. 81971985 and 82272308).
Most phages—viruses infecting prokaryotes—inject their genomes via a tail structure.The central tail tube,composed of tail tube protein(TTP),typically forms conserved hexameric or trimeric rings.In this paper,we rep...
supported by grants from the China Mega-Project on Infectious Disease Prevention (No. 2013ZX10004-605, No. 2013ZX10004-607, No. 2013ZX10004-217, and No. 2011ZX10004-001);the National Hi-Tech Research and Development (863) Program of China (No. 2014AA021402, 2012AA022-003);the National Natural Science Foundation of China (No. 81572045)
Methicillin-resistant Staphylococcus aureus(MRSA) is an increasing cause of serious infection,both in the community and hospital settings. Despite sophisticated strategies and efforts, the antibiotic options for treat...
supported by the National Natural Science Foundation of China (41006087,91028001 and 41076063);the MEL Young Scientist Visiting Fellowship (MELRS0931);the Key Science and Technology Project of Fujian Province,China (2009Y0044)
Viruses are the most abundant biological entities in marine ecosystems.Most of them are phages that infect bacteria and archaea.Phages play important roles in causing the mortality of prokaryotic cells,structuring mic...