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相关机构：陕西师范大学郑州大学更多>>
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Acid-base and lipophilic properties of peptide nucleic acid derivatives
《Journal of Pharmaceutical Analysis》2021年第5期638-645,共8页Pramod Thakare Francesca Vasile Maura Vallaro Sonja Visentin Giulia Caron Emanuela Licandro Silvia Cauteruccio 
Pramod Thakare thanks the University of Milan for the Ph.D.fellowship.Giulia Caron,Maura Vallaro and Sonja Visentin acknowledge the financial support from the University of Turin(Ricerca Locale ex-60%,Bando2019).
The first combined experimental and theoretical study on the ionization and lipophilic properties of peptide nucleic acid(PNA)derivatives,including eleven PNA monomers and two PNA decamers,is described.The acidity con...
关键词：Peptide nucleic acids Ionization properties Potentiometric pH titration Immobilized artificial membrane CHROMATOGRAPHY LIPOPHILICITY 
Determination of pKa values of alendronate sodium in aqueous solution by piecewise linear regression based on acid-base potentiometric titration被引量：2
《Journal of Pharmaceutical Analysis》2016年第6期404-409,共6页Jing Ke Hanfei Dou Ximin Zhang Dushimabararezi Serge Uhagaze Xiali Ding Yuming Dong 
the support of Key Laboratory of Chinese Medicine Preparation of Solid Dispersion,Gansu Longshenrongfa Pharmaceutical Industry Co.,Ltd.,Gansu Province,China
As a mono-sodium salt form of alendronic acid,alendronate sodium presents multi-level ionization for the dissociation of its four hydroxyl groups.The dissociation constants of alendronate sodium were determined in thi...
关键词：Dissociation CONSTANTS ALENDRONATE SODIUM Distribution curve Piecewise linear regression ACID-BASE POTENTIOMETRIC TITRATION 
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