ALENDRONATE

作品数：41被引量：98H指数：6
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相关领域：医药卫生更多>>
相关作者：于世凤王晓敏杨宗萍李娜王林更多>>
相关机构：吉林大学北京大学第一医院北京大学口腔医院航空工业中心医院更多>>
相关期刊：《Open Journal of Orthopedics》《中华医学信息导报》《Case Reports in Clinical Medicine》《Open Journal of Preventive Medicine》更多>>
相关基金：国家自然科学基金教育部留学回国人员科研启动基金更多>>
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A comparison of the effect of alendronate and You-Gui-Wan on osteoporosis in female rats with kidney-yang deficiency
《Traditional Medicine Research》2024年第6期31-41,共11页Mei-Mei Wu Xing-Peng He Wan-Ting Wu Wen-Jie Lu Yan-Yang Mai Kun-Cai Xu Yao-Feng Zhi Hai-Xin Mo Jia-Di He Xin Zhang Peng-Fei Li 
supported by the National Natural Science Foundation of China(Grant No.81673996,81904220);the Jiangmen Association for Science and Technology-Youth science and technology talent lifting project(Grant No.2022-2023).
Background:In traditional Chinese medicine,You-Gui-Wan(YGW)is typically used to treat osteoporosis associated with kidney-yang deficiency.However,there have been few mechanistic studies on the effectiveness of kidney-...
关键词：OSTEOPOROSIS kidney-yang deficiency You-Gui-Wan ALENDRONATE 
H_(2)O_(2) actuated molybdenum oxide nanodots:Multi-enzyme-like activities,leverage of Fenton reaction,and dual-mode sensitive detection of alendronate sodium被引量：1
《Nano Research》2023年第10期12106-12115,共10页Siqi Wang Yao Jin Wenhui Ai Xiufeng Wang Zhiqing Zhang Ting Zhou Guodong Zhang Fang Wang 
National Natural Science Foundation of China(No.21603276);Fundamental Research Funds for the Central Universities(Nos.19CX02060A and 22CX03024A);the Natural Science Foundation of Shandong Province(No.ZR2022MB148).
Unexpected benefits to the catalytic performance of materials often originate from the presence of surface defects.Here,novel Dpenicillamine modified molybdenum oxide nanodots,with abundant oxygen vacancy defects,were...
关键词：nanozyme molybdenum oxide Fenton reaction alendronate sodium multi-enzyme-like activities 
Effects of alendronate on bone mass and organ pathology in ovariectomized mice
《Journal of Hainan Medical University》2023年第4期19-26,共8页WANG Long-fei GAO Yu-hai YANG Shi-chao HUANG Rui-xin LI Xing YANG Yutian XUAN Ying-ying TANG Han-qin CHEN Ke-ming 
General program of National Natural Science Foundation of China(81770879);Gansu Youth Science and Technology Fund Program(20JR5RA589);Joint Service Support Force 940 Hospital Laboratory Cultivation Project(2021yxky081)。
Objective:To investigate the effect of alendronate on bone mass and organ pathology of ovariectomized mice.Methods:Thirty SPF grade C57 female mice were randomly divided into three groups(n=10):Sham operation group(Sh...
关键词：Alendronate sodium Organ pathology Bone mineral density BIOMECHANICS Bone metabolism 
Effects of alendronate sodium combined with InterTan on osteoporotic femoral intertrochanteric fractures and fracture recurrence被引量：7
《World Journal of Clinical Cases》2022年第21期7324-7332,共9页Ke-Meng Wang Shi-Ping Wei Xiao-Yan Yin Qing-Ju Meng Yu-Ming Kong 
Supported by Special Projects for Social Development Areas.
BACKGROUND Osteoporosis is a global disease affecting 6.6%of the total population.Osteoporosis complications include fractures,increased bone fragility,and reduced bone strength.The most commonly affected parts are th...
关键词：Alendronate sodium InterTan treatment Osteoporotic femoral intertrochanteric fractures Bone mineral density Hip joint function 
Sodium alendronate loaded poly(L-lactideco-glycolide)microparticles immobilized on ceramic scaffolds for local treatment of bone defects
《Regenerative Biomaterials》2021年第3期22-31,共10页Łucja Rumian Cornelia Wolf-Brandstetter Sina Ro¨ßler Katarzyna Reczynska Hanna Tiainen Ha˚vard JHaugen Dieter Scharnweber Elzbieta Pamuła 
This work was supported by National Science Centre,Poland(2013/09/N/ST8/00309);Norwegian Research Council(228415);BMBF,Germany(GoBone German-Polish bilateral project 01DS16010A)。
Bone tissue regeneration in critical-size defects is possible after implantation of a 3D scaffold and can be additionally enhanced once the scaffold is enriched with drugs or other factors supporting bone remodelling ...
关键词：ceramic scaffolds sodium alendronate osteoblasts osteoclastogenesis collagen critical-size defect poly(L-lactideco-glycolide) MICROPARTICLES 
The Release Behavior,Biocompatibility and Physical Properties of Aid-loaded Strontium Doped Calcium Phosphate Cement被引量：2
《Journal of Bionic Engineering》2020年第6期1209-1223,共15页Maryam Mohammadi Sayed Mahmood Rabiee Saeed Hesaraki 
Iran National Science Foundation(INSF)for the research under Grant No.96015802.
The effect of concurrent attendance of two inhibitors of bone degradation,namely Alendronate(Aid)sodium trihydrate and Strontium(Sr),on Calcium Phosphate Cement(CPC)characteristics was explored.To this aim,5 wt%Stront...
关键词：calcium phosphate cements drug release alendronate sodium trihydrate STRONTIUM RAW264.7 cell G cell 
Sodium alendronate loaded poly(L-lactideco-glycolide)microparticles immobilized on ceramic scaffolds for local treatment of bone defects被引量：8
《Regenerative Biomaterials》2020年第3期293-302,共10页Lucja Rumian Cornelia Wolf-Brandstetter Sina Roβler Katarzyna Reczynska Hanna Tiainen Havard J.Haugen Dieter Scharnweber Elzbieta Pamula 
supported by National Science Centre,Poland(2013/09/N/ST8/00309);Norwegian Research Council(228415);BMBF,Germany(GoBone German-Polish bilateral project 01DS16010A).
Bone tissue regeneration in critical-size defects is possible after implantation of a 3D scaffold and can be additionally enhanced once the scaffold is enriched with drugs or other factors supporting bone remodelling ...
关键词：ceramic scaffolds sodium alendronate osteoblasts osteoclastogenesis collagen critical-size defect poly(L-lactideco-glycolide) MICROPARTICLES 
Alendronate loaded graphene oxide functionalized collagen sponge for the dual effects of osteogenesis and anti-osteoclastogenesis in osteoporotic rats被引量：13
《Bioactive Materials》2020年第4期859-870,共12页Yuyang Zeng Muran Zhou Lifeng Chen Huimin Fang Shaokai Liu Chuchao Zhou Jiaming Sun Zhenxing Wang 
supported by the National Key R&D Program of China(2019YFA0110500);the National Natural Science Foundation of China(81701922,81873941).
Graphene Oxide(GO)-related hydrogels have been extensively studied in hard tissue repair,because GO can not only enhance the mechanical properties of polymers but also promote osteogenic differentiation of mesenchymal...
关键词：Osteoporosis Osteoporotic bone defect Graphene oxide OSTEOCLAST ALENDRONATE 
Effectiveness associated with different therapies for senile osteoporosis: a network Meta-analysis被引量：9
《Journal of Traditional Chinese Medicine》2020年第1期17-27,共11页Wang Haixia Mo Shu Yang Li Wang Panpan Sun Kehuan Xiong Yingquan Liu Hengrui Liu Xiaoguang Wu Zhidi Ou Ling Li Xiaoyun Peng Xunqian Peng Bojia He Haibin Tian Ya Zhang Ronghua Zhu Xiaofeng 
Supported by the National Natural Science Foundation of China"Kidney Health Bone,Marrow Link Brain",a Study of Chinese Nourishing Kidney Herbs’Mechanism of Treatment of Osteoporosis Based on Neuropeptide Network;"Too Salty to Hurt the Bone",A Study on the Molecular Mechanism of High Salt Affecting Bone Metabolism Based on Related Ion Channels and Intervention of A Compound Chinese Medicine for Reinforcing Kidney(No.81473509,81673837).
OBJECTIVE:The aim of this study was to evaluate the effectiveness of Chinese herbal medicines for invigorating the kidney(CHMIK)on senile osteoporosis.METHODS:We searched for studies in English-language databases(Pub ...
关键词：OSTEOPOROSIS Aged Reinforcing KIDNEY Traditional Chinese DRUGS ALENDRONATE Calcium CALCITONIN Network Meta-analysis 
Alendronate disturbs femoral growth due to changes during immunolocalization of transforming growth factor-β1 and bone morphogenetic protein-2 in epiphyseal plate被引量：2
《World Journal of Experimental Medicine》2020年第1期1-9,共9页Juliana Souza Vieira Emanuelle Juliana Cunha Juliana Feltrin de Souza Luis Henrique Koeler Chaves Jessica Lakes de Souza Allan Fernando Giovanini 
BACKGROUND The epiphyseal growth plate is an important anatomical segment localized on the ends of a long bone.Despite the abovementioned atractive reasons for alendronate’s use,few data on the effect of alendronate ...
关键词：ALENDRONATE Bone development Epiphyseal plate Bone morphogentic protein-2 Transforming growth factor-β1 
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