supported by the Beijing High-Level Public Health Technical Talent Training Program(discipline backbone talent-02-32),the National Natural Science Foundation of China(No.81871586),and the Beijing Municipal Administration of Hospitals Incubating Program(PX2021066).
Background and Aims:Portal vein thrombosis(PVT)is a challenging complication in liver cirrhosis,with no currently available sensitive diagnostic markers.This study aimed to investigate the potential of neutrophil extr...
funded by the National Institute for Health Research(NIHR)Surgical Reconstruction and Microbiology Research Centre and the Scar Free Foundation.JML is supported by the NIHR Birmingham Biomedical Research Centre and the Medical Research Council(MRC)Versus Arthritis Centre for Musculoskeletal Ageing Research.The funding bodies had no role in the design of the study,the collection,analysis or interpretation of the data or in the writing of the manuscript.
Background:Traumatic injury is associated with increased concentrations of cell-free DNA(cfDNA)in the circulation,which contribute to post-injury complications.The endonuclease deoxyribonuclease 1(DNase-1)is responsib...
supported by grants from the International Islamic University Malaysia,the research management centre(No.IIUM/504/5/29/1)
Objective Nephrolithiasis is one of the most common disorders of the urinary tract. The aim of this study was to examine a possible relationship between DNase Ⅰ/Ⅱ activity and E3 SUMO-protein ligase NSE2 in the sera...
During C. elegans apoptosis, the dicer ribonuclease (DCR-1) is cleaved by the cell death protease CED-3 to generate a truncated DCR-1 (tDCR-1) with one and a half ribonuclease III (RNase III) domains, converting...
Objective To explore the inhibitory effect of recombinant human deoxyribonuclease on clotting phenomena and microaggregate formation of thawed and processed cord blood hematopoietic progenitors. Methods Six UCB sample...
Background Previous studies have suggested that interrupted clearance of nuclear DNA-protein complexes after cell death might initiate and propagate systemic lupus erythematosus (SLE). Deoxyribonuclease Ⅰ (DNaseⅠ) ...