Objective To evaluate the prevalence and one-year prognosis associated with frailty in a contemporary cohort of older patients with non-ST-elevation acute coronary syndrome(NSTEACS).Methods The IMPACT-TIMING-GO regist...
Objective To assess the prognostic impact of a routine invasive strategy according to the frailty burden in patients with non-ST-segment elevation myocardial infarction(NSTEMI)from the MOSCA-FRAIL clinical trial.Metho...
supported by the Traditional Chinese Medicine Scientific Research Project of Shanghai National Health Commission(No.2022QN017);the Science and Technology Commission of Shanghai Municipality(No.17dz2307500);Shanghai Municipal Commission of Health(the“Flagship”Department Construction Project of Integrated Traditional Chinese and Western Medicine for Geriatrics 2024)。
Aging is the greatest risk factor for cardiovascular disease(CVD),which is the most common cause of death in European countries.[1]It is estimated that during the period from 2020 to 2022,there were 9.0%more excess de...
With global improvements in life expectancy,the proportion of the world’s population over 60 years of age has grown by 3%annually,and it is expected that by 2050,this population segment will nearly double.[1]This dem...
BACKGROUND Acute coronary syndrome(ACS)is linked to a range of in-hospital complications,and age is recognized as risk factor for adverse events.Discrepancies between physiological and chronological age are explained ...
the National Key R&D Program of China(2020YFC2004800).
The present protocol describes an observational cohort study that was designed to propose a therapeutic scheme and formulate an individualized treatment strategy for frail elderly patients diagnosed with multiple dise...
found by statutory work number 3.19/III/18, National Institute of Cardiology, Warsaw, Poland.
BACKGROUND Frailty is associated with adverse events in elderly patients with acute coronary syndrome(ACS).Our aim was to compare the prognostic value of four frailty scales in patients aged≥65 years hospitalized wit...
Aortic stenosis(AS)is the most common valvular disease in the western coun-tries and is associated with aging.[1,2]Transcatheter aortic valve replacement(TAVR)now offers a therapeutic option for elderly patients who a...
supported by Mayo Clinic Foundation for Education and Research.
OBJECTIVE Older adults with coronary artery disease(CAD)are at risk for frailty.However,little is known regarding transition in frailty measures over time or its impact on outcomes.We sought to determine the associati...
supported by grant R01HL126911 from the National Heart,Lung,and Blood Institute;supported by grants R01HL137734,R01HL137794,R01HL13660,and R01HL141434。
Background Atrial fibrillation(AF) and heart failure(HF) frequently co-occur in older individuals. Among patients with AF, HF increases risks for stroke and death, but the associations between HF and incident cognitio...