The December 2023 issue of the Military Medical Research brings out an astounding discover y by Xu et al.[1]demonstrating a key role of the mysterious enzyme ADPdependent glucokinase(ADPGK)in the cellular metabolism o...
National Key R&D Plan(2023YFC3403200);National Natural Science Foundation of China(82070784,81702536,81974099 and 82170785);Science&Technology Department of Sichuan Province,China(2022JDRC0040,21GJHZ0246);Young Investigator Award of Sichuan University 2017(2017SCU04A17);Sichuan University-Panzhihua Science and Technology Cooperation Special Fund(2020CDPZH-4);China Postdoctoral Science Foundation(2021M692306);Post-Doctor Research Project of West China Hospital of Sichuan University(2021HXBH025).
Background Cell metabolism plays a pivotal role in tumor progression,and targeting cancer metabolism might effectively kill cancer cells.We aimed to investigate the role of hexokinases in prostate cancer(PCa)and ident...