supported by Grants from the C1 Gas Refinery Program,funded by the Ministry of Science and ICT(NRF-2018M3D3A1A01056181);the Enzyme engineering for next generation biorefinery(NRF-2022M3J5A1056169 and NRF-2022M3J5A1085239)from National Research Foundation(NRF);the Korea Research Institute of Bioscience and the Biotechnology(KRIBB)Research Initiative Program.
The bioconversion of 4-hydroxy-2-keto acid derivatives via aldol condensation of formaldehyde and pyruvate has received substantial attention as potential source of chemicals for production of amino acids,hydroxy carb...