OLIGOMERIZATION

作品数：93被引量：184H指数：7
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相关领域：理学生物学更多>>
相关作者：邹正升李保森黄昂孙颖张永杰更多>>
相关机构：北京大学华中科技大学弗吉尼亚大学中国科学技术大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金福建省自然科学基金更多>>
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Control of H_(2)S synthesis by the monomer-oligomer transition of OsCBSX3 for modulating rice growth-immunity balance
《Molecular Plant》2025年第2期350-365,共16页Haimiao Zhang Baolong Sun Muhammad Zunair Latif Yang Liu Lei Lv Tao Wu Yang Li Ziyi Yin Chongchong Lu Haipeng Zhao Lingguang Kong Xinhua Ding 
supported by the National Natural Science Foundation of China(32272557 and 32072500);the Major Basic Research Project of the Natural Science Foundation of Shandong Province(ZR2022ZD23 and ZR2024ZD07);the Shandong Province Key Research and Development Plan(2024CXGC010908 and 2024LZGCQY009);the Taishan Scholar Program of Shandong Province(tstp20221117);the“First Class Discipline"Construction Project of Shandong Agricultural University(811)。
Hydrogen sulfide(H_(2)S)is recognized as an important gaseous signaling molecule,similar to nitric oxide and carbon monoxide.However,less is known about the biosynthetic mechanism of H_(2)S in plants and its role in p...
关键词：hydrogen sulfide bacterial leaf streak bacterial blight Xanthomonas oryzae OLIGOMERIZATION 
Targeting STING oligomerization with licochalcone D ameliorates STING-driven inflammatory diseases
《Science China(Life Sciences)》2024年第12期2664-2677,共14页Yinghui Zhang Yadan Liu Bing Jiang Lifan Chen Jie Hu Buying Niu Jie Chang Zisheng Fan Jingyi Zhou Yajie Wang Dan Teng Ning Ma Xiaofeng Wang Ruirui Yang Mingyue Zheng Sulin Zhang 
financial support from National Natural Science Foundation of China (T2225002,82273855,82304379,81903639);National Key Research and Development Program of China (2022YFC3400504);the Youth Innovation Promotion Association CAS (2023296);the SIMM-SHUTCM Traditional Chinese Medicine Innovation Joint Research Program (E2G805H);the open fund of state key laboratory of Pharmaceutical Biotechnology,Nanjing University,China (KF-202301);the Natural Science Foundation of Shanghai (22ZR1474300);Lingang Laboratory (LG202102-01-02,LG-QS-202204-01);Young Elite Scientists Sponsorship Program by CAST (2023QNRC001)。
The development of STING inhibitors for the treatment of STING-related inflammatory diseases continues to encounter significant challenges.The activation of STING is a multi-step process that includes binding with c G...
关键词：cGAS-STING signaling STING inhibitor Transformer CPI model Licochalcone D inflammatory diseases 
Ni/ZSM-5 Catalysts for Light Olefin Oligomerization:Effects of Supports and Ni Sites on Activity and Selectivity
《China Petroleum Processing & Petrochemical Technology》2024年第3期15-23,共9页Zuo Qi Liang Ke Ma Yirong Jia Yangxiao Liao Mingjie Zheng Jiajun Li Ruifeng Li Wenlin 
Financial support was obtained from the State Key Laboratory of Petroleum Molecular&Process Engineering(24-ZC0607-0099);the Natural Science Foundation of China(21706177 and 22378293).
A series of Ni/ZSM-5 containing a small amount of Ni was prepared by an ion exchanged method.The impact of the n(SiO_(2))/n(Al_(2)O_(3))ratio on the catalytic activity was studied using the samples 0.09Ni/ZSM-5(60)and...
关键词：nickel ZEOLITE acid sites OLIGOMERIZATION catalyst 
Evaluation of laboratory and environmental exposure systems for protein modification upon gas pollutants and environmental factors
《Journal of Environmental Sciences》2024年第9期213-223,共11页Zhiwei Pan ShiyiWu Qiaoze Zhu Fobang Liu Yongjian Liang Chenglei Pei Haoyu Jiang Yingyi Zhang Senchao Lai 
supported by the National Natural Science Foundation of China(Nos.41975156,41675119)。
Chemical modifications of proteins induced by ambient ozone(O_(3))and nitrogen oxides(NOx)are of public health concerns due to their potential to trigger respiratory diseases.The laboratory and environmental exposure ...
关键词：Protein modification Laboratory simulation Environmental exposure OLIGOMERIZATION NITRATION 
Oligomerization of drug transporters:Forms,functions,and mechanisms
《Acta Pharmaceutica Sinica B》2024年第5期1924-1938,共15页Chunxu Ni Mei Hong 
This work was supported by Natural Science Foundation of Guangdong Province(grant number 2022A1515010552,China);National Natural Science Foundation of China(grant number U1832101 and 81373473).
Drug transporters are essential players in the transmembrane transport of a wide variety of clinical drugs.The broad substrate spectra and versatile distribution pattern of these membrane proteins infer their pharmaco...
关键词：Drug development Drug transporters OLIGOMERIZATION Protein expression Protein–protein interaction Regulatory mechanism Structural basis Transport function 
Inhibiting the oligomerization of mycobacterial DNA-directed RNA polymerase(RNAP)using natural compound via in-silico techniques
《Medicine in Novel Technology and Devices》2024年第1期97-109,共13页Ehssan H.Moglad 
We appreciate Prince Sattam bin Abdulaziz University for funding this project(PSAU/2023/R/1444).
Mycobacterium tuberculosis(Mtb)is responsible for the spread of tuberculosis(TB).The current study employed virtual screening of 2569 natural compounds against the DNA-directed RNA polymerase(RNAP)of Mtb to identify t...
关键词：Mycobacterium tuberculosis DNA-Directed RNA polymerase DOCKING Steered MD simulation Natural compounds Binding free energy Umbrella sampling 
MCM-22 zeolite-based system to produce jet fuel from the 1-hexene oligomerization
《Carbon Resources Conversion》2024年第1期71-78,共8页Hao Yang Qi Zuo Xin Ning Jiajun Zheng Wenlin Li Ruifeng Li 
Financial support from the Natural Science Foundation of China(21706177 and U19B2003);Guangxi Key Laboratory of Green Chemical Materials and Safety Technology,Beibu Gulf University(2022SYSZZ04);China Petroleum&Chemical Corporation(121014-2).
The oligomerization of light olefins is an alternative for generating clean liquid fuels.In this study,the MCM-22 zeolite featuring a partially disordered layered structure with framework combined 10 membered ring(10 ...
关键词：Jet fuels OLIGOMERIZATION Zeolites MCM-22 Reaction order 
Mechanism Study of BF_(3)/n-Butanol-catalyzed 1-Decene Oligomerization Reaction
《China Petroleum Processing & Petrochemical Technology》2023年第2期74-80,共7页He Leilei Su Shuo Zhao Yi Xu Bing Long Jun 
This work was financially supported by China Petrochemical Corporation Project(120055).
The active catalysts of the BF_(3)/n-C_(4)H_(9)OH-catalyzed 1-decene oligomerization reaction,as well as the distribution of the reaction products,was investigated by molecular simulation.The calculation results show ...
关键词：poly-α-olefin synthetic base oil oligomerization reaction reaction mechanism boron trifluoride 
Competing esterification and oligomerization reactions of typical long-chain alcohols to secondary organic aerosol formation
《Journal of Environmental Sciences》2023年第4期103-112,共10页Jiaxin Wang Xiaohui Ma Yuemeng Ji Yongpeng Ji Yanpeng Gao Yuqi Xiao Guiying Li Taicheng An 
financially supported by the Natural Science Foundation of Guangdong Province,China (No.2019B151502064);the National Natural Science Foundation of China (Nos.42077189 and 4201001008);the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program (No.2017BT01Z032);the Innovation Team Project of Guangdong Provincial Department of Education(No.2017KCXTD012);the Science and Technology Key Project of Guangdong Province,China (No.2019B110206002)。
Organosulfate (OSA) nanoparticles,as secondary organic aerosol (SOA) compositions,are ubiquitous in urban and rural environments.Hence,we systemically investigated the mechanisms and kinetics of aqueous-phase reaction...
关键词：Long-chain alcohols Organosulfates Aqueous phase reaction Reaction mechanisms Secondary organic aerosol 
Targeting a novel inducible GPX4 alternative isoform to alleviate ferroptosis and treat metabolic-associated fatty liver disease被引量：13
《Acta Pharmaceutica Sinica B》2022年第9期3650-3666,共17页Jie Tong Dongjie Li Hongbo Meng Diyang Sun Xiuting Lan Min Ni Jiawei Ma Feiyan Zeng Sijia Sun Jiangtao Fu Guoqiang Li Qingxin Ji Guoyan Zhang Qirui Shen Yuanyuan Wang Jiahui Zhu Yi Zhao Xujie Wang Yi Liu Shenxi Ouyang Chunquan Sheng Fuming Shen Pei Wang 
supported by the grants from National Natural Science Foundation of China (82073915, 91849135, 81673485, 81773719, 81973312 and 81971306);National Key Research and Development Project (2018YFA0108301, China);Shanghai Science and Technology Commission Experimental Animal Grants (21XD1424900, 19140904700, 19140904900 and 21S11901200, China);Shanghai Shuguang Program (19SG32, China);Shanghai “Rising Stars of Medical Talent” Youth Development ProgramYouth Medical Talents-Clinical Pharmacist Program [SHWRS(2020)_087, China]
Metabolic-associated fatty liver disease(MAFLD),which is previously known as non-alcoholic fatty liver disease(NAFLD),represents a major health concern worldwide with limited therapy.Here,we provide evidence that ferr...
关键词：Ferroptosis GPX4 Alternative isoform Fatty liver OLIGOMERIZATION Methionine/choline-deficient diet High fat-fructose/sucrose diet Protein interaction 
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