MUCOADHESION

作品数:12被引量:23H指数:2
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相关领域:医药卫生化学工程更多>>
相关作者:黄爱文更多>>
相关机构:中国药科大学更多>>
相关期刊:《Asian Journal of Pharmaceutical Sciences》《Journal of Encapsulation and Adsorption Sciences》《Asian Pacific Journal of Tropical Biomedicine》《Chinese Journal of Chemistry》更多>>
相关基金:国家自然科学基金中国博士后科学基金更多>>
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  • 学科=医药卫生—药剂学x
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Exploring the potential of functional polymer-lipid hybrid nanoparticles for enhanced oral delivery of paclitaxel被引量:1
《Asian Journal of Pharmaceutical Sciences》2021年第3期387-395,共9页Lu Qin Haiyang Wu Enyu Xu Xin Zhang Jian Guan Ruizhi Zhao Shirui Mao 
This research is financially supported by the Natural Science Foundation of China(Grant No.81273446).
Most biopharmaceutics classification system(BCS)class IV drugs,with poor solubility and inferior permeability,are also substrates of P-glycoprotein(P-gp)and cytochrome P450(CYP450),leading to their low oral bioavailab...
关键词:Polymer-lipid hybrid nanoparticles (PLHNs) Chitosan P-gp inhibitors CYP450 inhibitors MUCOADHESION Oral bioavailability 
Designing the new generation of intelligent biocompatible carriers for protein and peptide delivery被引量:11
《Acta Pharmaceutica Sinica B》2018年第2期147-164,共18页Angela M.Wagner Margaret P.Gran Nicholas A.Peppas 
supported in part by a grant from the National Institutes of Health (R01-EB-00246020);the Cockrell Family Regents Chair. Angela M.Wagner was supported by a National Science Foundation Graduate Research Fellowship (DGE-1610403);the S.E.S.H.A. Endowed Graduate Fellowship in Engineering;the Philanthropic Educational Organization Scholar Award
Therapeutic proteins and peptides have revolutionized treatment for a number of diseases, and the expected increase in macromolecule-based therapies brings a new set of challenges for the pharmaceutics field. Due to t...
关键词:Oral delivery HYDROGELS Protein delivery Peptide delivery Carbohydrates MUCOADHESION 
Topical delivery of acetazolamide by encapsulating in mucoadhesive nanoparticles被引量:1
《Asian Journal of Pharmaceutical Sciences》2017年第6期550-557,共8页Satish Manchanda Pravat Kumar Sahoo 
The intent of this study was to provide topical delivery of acetazolamide by preparing chitosan-STPP (sodium tripolyphosphate) nanoparticles of acetazolamide and evaluate the particle size, zeta potential, drug entrap...
关键词:ACETAZOLAMIDE CHITOSAN STPP OCULAR hypertension MUCOADHESION 
A clinical perspective on mucoadhesive buccal drug delivery systems被引量:1
《The Journal of Biomedical Research》2014年第2期81-97,共17页Ritu M Gilhotra Mohd Ikram Sunny Srivastava Neeraj Gilhotra 
Mucoadhesion can be defined as a state in which two components, of which one is of biological origin, are held together for extended periods of time by the help of interfacial forces. Among the various transmucosal ro...
关键词:buccal mucosa clinical perspective MUCOADHESION patents transmucosal route 
Formulation of unidirectional release buccal patches of carbamazepine and study of permeation through porcine buccal mucosa被引量:1
《Asian Pacific Journal of Tropical Biomedicine》2013年第12期995-1002,共8页Parthasarathy Govindasamy Bhaskar Reddy Kesavan Jayaveera Korlakunta Narasimha 
supported by RR college of Pharmacy affiliated to Rajiv Gandhi University of Health Sciences,Bangalore,India(Grant No.RRCP\PCEUTICS\IHR&D\231)
Objective:To achieve transbuccal release of carbamazepine by loading in unidirectional release mucoadhesive buccal patches.Methods:Buccal patches of carbamazepine with unidirectional drug release were prepared using h...
关键词:BUCCAL PATCHES CARBAMAZEPINE MUCOADHESION Biaxially-oriented polypropylene films PORCINE BUCCAL MUCOSA 
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