supported by grants from the National Natural Science Foundation of China (81471620, 81671627, 81571606, 81172876, U0832601);the 13th Five-Year Key Scientific and Technological Program of China (2017ZX10304402-002-004, 2017ZX10202102-001-005);the Knowledge Innovation Program of the Chinese Academy of Sciences (KJZD-EW-L1002, KSCX2-EW-R-13);the National Key Research & Development Plan (2016YFC1201000);the National Basic Research Program of China (2012CBA01305)
TRIM5α restricts retroviruses in a species-specific manner. Cyclophilin A was independently retrotransposed into the TRIM5 loci in different species, leading to the generation of antiviral TR1M5-cyclophilin A (TRIM...
partly supported by grants from the National Natural Science Foundation of China(81471620;81671627;81571606;81601808;81172876;U0832601);the National Basic Research Program of China(2012CBA01305);the 13th Five-Year Key Scientific and Technological Program of China(2017ZX10304402-002-004;2017ZX10202102-001-005);the National Key Research & Development(R&D)Plan(2016YFC1201000)
Parasites can increase infection rates and pathogenicity in immunocompromised human immunodeficiency virus (HIV) patients. However, in vitro studies and epidemiological investigations also suggest that parasites mig...
supported by the National Basic Research Program of China (2012CBA01305);the National Natural Science Foundation of China (81172876; 81571606; 81471620; U0832601; 30671960);the 13th Five-Year Key Scientific and Technological Program of China (2017ZX10304402002-004; 2017ZX10202102-001-005);the Knowledge Innovation Program of the Chinese Academy of Sciences (KSCX2-EW-R-13; KJZD-EW-L10-02; CASIMM0320163020);the National Key Research & Development Plan (2016YFC1201000);Yunnan Applicative and Basic Research Program (2014FB181; 201501PH00015)
Viral reservoirs of HIV-1 are a major obstacle for curing AIDS. The novel animal models that can be directly infected with HIV-I will contribute to develop effective strategies for eradicating infections. Here, we ino...
Dear Editor, Germ cell transplantation and testicular tissue grafting have been developed for male fertility restoration. The testis tissue from young mammals, including mice and monkeys, is capable of undergoing com...
supported in part by the Key Scientific and Technological Program of China(2012ZX10001-007;2013ZX10001-002);the National Basic Research Program of China(2012CBA01305);the National Natural Science Foundation of China(81172876;81273251;U1202228);the Knowledge Innovation Program of CAS(KSCX2-EW-R-13;KJZD-EW-L10-02)
The complex and dynamic vaginal microbial ecosystem is critical to both health and disease of the host. Studies focusing on how vaginal microbiota influences HIV-1 infection may face limitations in selecting proper an...
the National Foundation for Natural Sciences of China and the National Key Basic Research Program (dubbed the National "973 Program")
Recent studies made by CAS scientists may shed new light on a novel approach to demystifying the complicated pathogenesis of AIDS, i.e., the formative mechanism of HIV infection at the molecular level. Their pioneerin...