BERGENIN

作品数:13被引量:41H指数:4
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相关作者:张晓云史彦斌倪京满周兴旺赵全义更多>>
相关机构:厦门大学中国科学院云南大学兰州大学更多>>
相关期刊:《Journal of Pharmaceutical Analysis》《中国生物学文摘》《Journal of Integrative Medicine》《Asian Pacific Journal of Tropical Medicine》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划广东省自然科学基金广州市天河区科技计划项目更多>>
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Comparative pharmacokinetics of bergenin,a main active constituent of Saxifraga stolonifera Curt.,in normal and hepatic injury rats after oral administration被引量:10
《Chinese Journal of Natural Medicines》2016年第10期776-782,共7页PAN Rong-Hua HE Hong-Mei DAI Yue XIA Yu-Feng 
supported by Health Innovation Personnel Training Project of Changzhou City(No.CWKJ 2010-368);Changzhou High Level Health Personnel Training Project
Bergenin, isolated from the herb of Saxifrage stolonifera Curt.(Hu-Er-Cao) has hepatoprotective, anti-inflammatory, antitussive, and neuroprotective activities. The aim of the present study was to establish a simple, ...
关键词:BERGENIN Saxifrage stolonifera Curt HPLC PHARMACOKINETIC Hepatic injury 
Synthesis and cytotoxic activity of 3, 4, 11-trihydroxyl modified derivatives of bergenin被引量:3
《Chinese Journal of Natural Medicines》2014年第12期929-936,共8页YAN De-Biao ZHANG Dong-Ping LI Ming LIU Wen-Yuan FENG Feng DI Bin GUO Qing-Long XIE Ning 
supported by the Natural Science Foundation of China(Nos.81274064 and 81373956);the National Fund for Fostering Talents of Basic Science(NFFTBS)(No.J1030830);the Science and Technology Supporting Project of Xinjiang(No.201291160)
To synthesize a series of 3-, 4-, and/or 11-trihydroxy modified bergenin derivatives and evaluated their cytotoxic activity in vitro. The phenolic hydroxyl groups of bergenin were protected by benzyl groups with benzy...
关键词:BERGENIN 3- 4- and/or 11-trihydroxyl modified derivatives Cytotoxic activity Structure-activity relationships 
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