Study on the efficacy and safety of tenofovir alafenamide in treating chronic hepatitis B patients with poor entecavir response,No.SKJP22020201008.
BACKGROUND Entecavir(ETV)is a potent and safe antiviral agent for patients with chronic hepatitis B(CHB);however,some patients may exhibit suboptimal response or resistance to ETV.Tenofovir alafenamide(TAF)is a novel ...
BACKGROUND Entecavir(ETV)is a potent and selective nucleotide analog with significant activity against hepatitis B virus(HBV).ETV maleate is a derivative compound of ETV and was reported to have an efficacy and safety...
Natural Science Foundation of Fujian Province,No.2019J01593;High-Level Talent Innovation Project of Quanzhou,No.2018C067R;Science and Technology Innovation Joint Project of Fujian Province,No.2019Y9048;Youth Research Project of Fujian Provincial Health Commission,No.2018-1-94 and No.2018-1-95;Science and Technology Project of Quanzhou,No.2018Z074 and No.2018Z069.
BACKGROUND The incidence of hepatocellular carcinoma(HCC)is high in China,and approximately 15%-20%of HCC cases occur in the absence of cirrhosis.Compared with patients with cirrhotic HCC,those with non-cirrhotic HCC ...