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Efficacy and Safety of Lianhua Qingke Tablets in the Treatment of Long Coronavirus Disease (COVID) Cough: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Study
《Engineering》2024年第9期61-69,共9页Xiaolong Xu Jie Ying Taiping Tian Tengwen Liu Chunhua Chi Zhizhong Gong Jingpeng Gao Meiping Qian Wei Tan Ran Cao Shuixian Lv Zhougui Ling Shuo Wang Bo Li Qingquan Liu 
supported by National Multidisciplinary Innovation Team Project of Traditional Chinese Medicine(ZYYCXTD-D-202201);Beijing Key Specialized Department for Major Epidemic Prevention and Control(Construction Project;Jingweiyi[2019]161).
Lianhua Qingke tablets,a patented traditional Chinese medicine that has validated clinical efficacy for treating cough caused by severe acute respiratory syndrome coronavirus 2 infection,lack rigorous evidence-based r...
关键词：Long coronavirus disease(COVID)cough Traditional Chinese medicine Clinical trial Efficacy Safety 
Bifidobacterium longum CCFM1077 Attenuates Hyperlipidemia by Modulating the Gut Microbiota Composition and Fecal Metabolites:A Randomized,Double-Blind,Placebo-Controlled Clinical Trial
《Engineering》2023年第9期193-205,共13页Chuanqi Chu Jinchi Jiang Leilei Yu Yiwen Li Songli Zhang Wei Zhou Qun Wang Jianxin Zhao Qixiao Zhai Fengwei Tian Wei Chen 
supported by the Natural Science Foundation of Jiangsu Province(BK20220155 and BE2021623);the National Natural Science Foundation of China(32021005,U1903205,and 32001665);the Key Scientific and Technological Research Projects in the Key Areas of the Xinjiang Production and Construction Corps(2018AB010)。
An increasing number of studies have indicated that gut microbiota and its metabolites are crucial in the development of hyperlipidemia.Bifidobacterium longum(B.longum)CCFM1077 has been shown to have lipid-lowering ef...
关键词：PROBIOTICS Bifidobacterium longum HYPERLIPIDEMIA Gut microbiota Fecal metabolites Bile acid(BA) 
The Correlation Between Decreased Ornithine Level and Alleviation of Rheumatoid Arthritis Patients Assessed by a Randomized,Placebo-Controlled,Double-Blind Clinical Trial of Sinomenine被引量：5
《Engineering》2022年第9期93-99,共7页Ying Shi Hu-Dan Pan Jian-Lin Wu Qing-Hua Zou Xin-Yi Xie Hong-Gang Li Hua Zhou Xi-Qing Bian Wen-Fei Leng Can-Jian Wang Ya-Feng Wang Yong-Fei Fang Liang Liu 
financially supported by grants from the Macao Science and Technology Development Fund(0032/2018/AFJ,0003/2019/AKP,and 0010/2020/A1);the Key Program in Emerging Industry of the Hunan Department of Science&Technology(2014GK1058);funded by Dr.Neher’s Biophysics Laboratory for Innovative Drug Discovery(001/2020/ALC)supported by the Macao Science and Technology Development Fund。
Sinomenine(SIN)is commonly used as part of rheumatoid arthritis(RA)therapy in China,but there is still no published evidence of the efficacy of SIN monotherapy.This work investigates the efficacy and safety of SIN in ...
关键词：Rheumatoid arthritis SINOMENINE Efficacy Safety Inflammatory biomarker 
Lactobacillus plantarum CCFM8610 Alleviates Irritable Bowel Syndrome and Prevents Gut Microbiota Dysbiosis:A Randomized,Double-Blind,Placebo-Controlled,Pilot Clinical Trial被引量：3
《Engineering》2021年第3期376-385,共10页Yang Liu Xinjie Yu Leilei Yu Fengwei Tian Jianxin Zhao Hao Zhang Long Qian Qun Wang Zhengqing Xue Qixiao Zhai Wei Chen 
supported by the National Natural Science Foun-dation of China Program(31871773 and 31820103010);National Key Research and Development Project(2018YFC1604206);Projects of Innovation and Development Pillar Program for Key Industries in Southern Xinjiang of Xinjiang Production and Construction Corps(2018DB002);National First-Class Discipline Program of Food Science and Technology(JUFSTR20180102);the Biotechnology and Biological Sciences Research Council(BBSRC) Newton Fund Joint Centre Award;Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province.
Irritable bowel syndrome with diarrhea(IBS-D)is chronic intestinal dysfunction with diarrhea and othercomplicated clinical symptoms,and it has a great impact on the daily life and mental state of patients.Some studies...
关键词：Lactobacillus plantarum Irritable bowelsyndrome Gut microbiota Butyric acid Clinical trial 
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