ETHASELEN

作品数:9被引量:9H指数:2
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相关作者:曾慧慧傅佳凝谭强王立辉李静更多>>
相关机构:北京大学沈阳药科大学更多>>
相关期刊:《Journal of Chinese Pharmaceutical Sciences》《Acta Pharmacologica Sinica》《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金更多>>
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Ethaselen: a novel organoselenium anticancer agent targeting thioredoxin reductase 1 reverses cisplatin resistance in drug-resistant K562 cells by inducing apoptosis被引量:1
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2017年第5期373-382,共10页Suo-fu YE Yong YANG Lin WU Wei-wei MA Hui-hui ZENG 
supported in part by the National Natural Science Foundation of China(No.81372266);the National Science and Technology Major Project of the Ministry of Science and Technology of China(No.2011zx09101-001-03)
It has been reported that Ethaselen shows inhibitory effects on thioredoxin reductase(TrxR) activity and human tumor cell growth. In order to find an efficient way to reverse cisplatin resistance, we investigated th...
关键词:Cisplatin resistance CISPLATIN Bcl-2 Cytochrome c ETHASELEN 
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