We report a case of a 9-month-old girl diagnosed as heterozygous to the Chediak-Higashi syndrome (CHS) after the death of her four brothers, who had similar symptoms of severe anemia, recurrent infections, and multipl...
supported by the National Natural Science Foundation of China(31821001 and 32170528).
Inbreeding and loss of genetic diversity increase the extinction risk of small isolated populations.Genetic rescue by augmenting gene flow is a powerful means for the restoration of lost genetic variation.In this stud...
supported by Key-Area Research and Development Program of Guangdong Province(Grant No.2022B1111230001);National Natural Science Foundation of China(31860048).
Understanding genome-wide diversity,inbreeding,and the burden of accumulated deleterious mutations in small and isolated populations is essential for predicting and enhancing population persistence and resilience.Howe...
funded by the National Natural Science Foundation of China(NSFC,Grant No.31520103903 to Y.-H.Sun and J.Hoglund);the Biodiversity Conservation Project of the Second Forest and Grass Ecosystem Recovery(Grant No.QHTX-2021-016).
Genetic load and inbreeding are recognized as important factors to be considered in conservation programs.Elevated levels of both can increase the risk of population extinction by negatively impacting fitness-related ...
supported by the National Science Foundation Plant Genome Integrative Organismal Systems(IOS)Grant 2310230(Characterization of Haploid Induction in Potato);Grant 1956429(Variants and Recombinants without Meiosis).
Conversion of potato from a tetraploid, heterozygous, vegetatively propagated crop to a diploid F1hybrid, propagated via botanical seed, would constitute a considerable advance for global agriculture,but faces multipl...
funded by the Natural Science Foundations of China(No.32172702);National Key Research and Development Program of China(2021YFD1301101);Agricultural Science and Technology Innovation Program(ASTIP-IAS02)。
Background Genomic selection involves choosing as parents those elite individuals with the higher genomic estimated breeding values(GEBV)to accelerate the speed of genetic improvement in domestic animals.But after mul...
funded by the AGL-2017-84217-P Research project from Ministerio de Economia,Industria y Competitividad,Gobierno de Espana.
Background:Estimating inbreeding,which is omnipresent and inevitable in livestock populations,is a primary goal for management and animal breeding especially for those interested in mitigating the negative consequence...
supported by the“Second National Survey of Terrestrial Wildlife Project”(grant number:20080131);funded by National Forestry and Grassland Administration of China.
Identification of the effect of anthropogenic threats on ecosystem is crucial.We used molecular tools and remote sensing to evaluate the population status of an isolated Asian elephant population in southwestern China ...
Key Laboratory of Southwest China Wildlife Resources Conservation(Ministry of Education),China West Normal University(XNYB18-02);Nature Conservation of Snake Island and Laotieshan Mountain,Dalian,China(Y8Y3041).
Island species and their ecosystems play an important role in global biodiversity preservation,and many vulnerable island species are conservation priorities.Although insular habitat likely facilitates the species div...