Epilepsy affects all age groups and is one of the most common and disabling neurological disorders worldwide.Drug-resistant epilepsy(DRE),status epilepticus(SE),and sudden unexpected death in epilepsy(SUDEP),which are...
Background Various cardiac and autonomic manifestations are frequently reported during seizures.Among the seizure-related arrhythmia,ictal tachycardia is the most common,followed by ictal bradycardia,with ictal asysto...
the National Natural Science Foundation of China(81630098,82022071);the Starry Night Science Fund of the Zhejiang UniversityShanghai InstituteforAdvancedStudy(SN-ZJU-SIAS-0011).
The raphe nuclei comprise nearly all of 5-hydroxytryptaminergic(5-HTergic)neurons in the brain and are widely acknowledged to participate in the modulation of neural excitability.“Excitability-inhibition imbalance”r...
Background:The mechanism of sudden unexpected death in epilepsy remains poorly understood.Seizure induced cardiac arrhythmia,central and obstructive apneas have been proposed as possible causes of death.Here we report...