CYCLOPENTENONE

作品数：3被引量：2H指数：1
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相关期刊：《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《Chinese Chemical Letters》更多>>
相关基金：国家自然科学基金更多>>
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Chemodivergent annulations of allenyl imides andβ,γ-enones switched by nucleophilic phosphine and amine catalysts
《Chinese Chemical Letters》2024年第1期254-258,共5页Bingsen Xiang Yuhao Wang Chuqing Xiao Fengkai He Yiyong Huang 
the financial support for this investigation from the National Natural Science Foundation of China(No.22072111;the Fundamental Research Funds for the Central Universities(No.2023IVA055).
Nucleophilic phosphine and amine catalyst-switched chemodivergent[4+1]and[3+3]annulations of allenyl imides andβ,γ-enones have been developed,furnishing highly substituted 2-cyclopentenone and 2-pyranone derivatives...
关键词：Chemodivergent Nucleophilic catalysis ALLENE CYCLOPENTENONE Pyranone 
TFEB,a master regulator of autophagy and biogenesis,unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2被引量：1
《Acta Pharmacologica Sinica》2022年第5期1251-1263,共13页Chuan-bin Yang Jia Liu Benjamin Chun-Kit Tong Zi-ying Wang Zhou Zhu Cheng-fu Su Sravan Gopalkrishnashetty Sreenivasmurthy Jia-xi Wu Ashok Iyaswamy Senthilkumar Krishnamoorthi Shi-ying Huang King-ho Cheung Ju-xian Song Jie-qiong Tan Jia-hong Lu Min Li 
We would like to thank Prof.Richard J.Youle(US National Institute of Neurological Disorders and Stroke)and Prof.Myung-Shik Lee(Yonsei University College of Medicine)for providing TFEB knockout HeLa cells.We thank Martha Dahlen for the English editing.This study was supported by the Hong Kong General Research Fund(GRF/HKBU12101417,GRF/HKBU12100618);the National Natural Science Foundation of China(81703487,and 81773926);Shenzhen Science and Technology Innovation Commission(JCYJ20180302174028790,JCYJ20180507184656626);the Hong Kong Health and Medical Research Fund(HMRF17182541,HMRF17182551);research funds from Hong Kong Baptist University(HKBU/RC-IRCs/17-18/03).
Transcriptional factor EB(TFEB),a master regulator of autophagy and lysosomal biogenesis,is generally regarded as a pro-survival factor.Here,we identify that besides its effect on autophagy induction,TFEB exerts a pro...
关键词：transcriptional factor EB(TFEB) 15-deoxy-∆-12 14-prostaglandin J2(15d-PGJ2) autophagy and lysosome biogenesis ATF4 ER stress apoptosis 
Dalestones A and B, two anti-inflammatory cyclopentenones from Daldinia eschscholzii with an edited strong promoter for the global regulator LaeA-like gene被引量：1
《Chinese Journal of Natural Medicines》2019年第5期387-393,共7页ZHOU Zhen-Zhen ZHU Hong-Jie YANG Cheng-Long LIU Yan-Jun JIANG Nan XIAO Yong-Sheng SHI Li-Yun JIAO Rui-Hua GE Hui-Ming TAN Ren-Xiang 
supported by the National Natural Science Foundation of China(Nos.21672101,21702099 and 81673333)
Replacement of the native promoter of the global regulator Lae A-like gene of Daldinia eschscholzii by a strong gpdA promoter led to the generation of two novel cyclopentenone metabolites, named dalestones A and B, wh...
关键词：Daldinia eschscholzii Global REGULATOR CYCLOPENTENONE 
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