REGULATOR

作品数：374被引量：734H指数：12
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相关机构：第二军医大学华中农业大学中山大学孙逸仙纪念医院第三军医大学西南医院更多>>
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Regulator of G protein signaling 6 mediates exercise-induced recovery of hippocampal neurogenesis,learning,and memory in a mouse model of Alzheimer’s disease
《Neural Regeneration Research》2025年第10期2969-2981,共13页Mackenzie M.Spicer Jianqi Yang Daniel Fu Alison N.DeVore Marisol Lauffer Nilufer S.Atasoy Deniz Atasoy Rory A.Fisher 
supported by the National Institutes of Health,Nos.AA025919,AA025919-03S1,and AA025919-05S1(all to RAF).
Hippocampal neuronal loss causes cognitive dysfunction in Alzheimer’s disease.Adult hippocampal neurogenesis is reduced in patients with Alzheimer’s disease.Exercise stimulates adult hippocampal neurogenesis in rode...
关键词：adult hippocampal neurogenesis Alzheimer’s disease dentate gyrus EXERCISE learning/memory neural precursor cells regulator of G protein signaling 6(RGS6) 
Diagnostic value and immune infiltration characterization of WTAP as a critical m6A regulator in liver transplantation
《Hepatobiliary & Pancreatic Diseases International》2025年第2期138-146,共9页Shan-Shan Li Deng-Liang Lei Hua-Rong Yu Song Xiang Yi-Hua Wang Zhong-Jun Wu Li Jiang Zuo-Tian Huang 
supported by grants from Chongqing Re-search Performance Incentive and Guidance Project(No.cstc2022jxjl120032);Chongqing Technology Innovation and Application Development(Key Project,No.cstc2021jscx-gksb X0060)。
Background:RNA N6-methyladenosine(m6A)regulators are essential for numerous biological processes and are implicated in various diseases.However,the comprehensive role of m6A regulators in the context of liver transpla...
关键词：Ischemia-reperfusion injury Liver transplantation N6-methyladenosine WTAP 
Dual-role regulator of a novel miR-3040 in photoperiod-mediated wing dimorphism and wing development in green peach aphid
《Insect Science》2025年第1期80-94,共15页Yun-Hui Zhang Xin Qian Xin Zong Shi-Heng An Shuo Yan Jie Shen 
the National Natural Science Foundation of China(32030012);National Key Research and Development Program of the Ministry of Science and Technology(2022YFD1401800).
Wing dimorphism is regarded as an important phenotypic plasticity involved in the migration and reproduction of aphids.However,the signal transduction and regulatory mechanism of wing dimorphism in aphids are still un...
关键词：miR-3040 Myzus persicae PHOTOPERIOD wing development wing dimorphism 
Investigating the Relationship between Age-Related Cardiac Hypertrophy, Skeletal Muscle Strength, and the FNDC5 Protein as a Potential Regulator
《Journal of Biosciences and Medicines》2025年第2期450-464,共15页Tao Feng Ziyang Fang Yinjun Luo Xin Zhang Ying Li Shijing Ma Jinting Wei Xiaoyan Fang Biao Li Lingling Huang Jinhua Wang Suchan Liao 
Background: Aging-induced cardiac hypertrophy and reduced skeletal muscle strength contribute to increased disease risk and life burden in the elderly. FNDC5 acts as a protective muscle factor in both cardiac and skel...
关键词：AGING Heart Hypertrophy Skeletal Muscle FNDC5 
RGS4 promotes the progression of gastric cancer through the focal adhesion kinase/phosphatidyl-inositol-3-kinase/protein kinase B pathway and epithelial-mesenchymal transition
《World Journal of Gastroenterology》2025年第2期113-127,共15页Peng-Yu Chen Pei-Yao Wang Bang Liu Yang-Pu Jia Zhao-Xiong Zhang Xin Liu Dao-Han Wang Yong-Jia Yan Wei-Hua Fu Feng Zhu 
Supported by the Fundamental Research Program of Shanxi Province,No.202203021222418;Research Program of Shanxi Provincial Health Commission,No.2023061;Fundamental Research Cooperation Program of Beijing-Tianjin-Hebei Region of Natural Science Foundation of Tianjin,No.22JCZXJC00140;Tianjin Major Science and Technology Project,No.21ZXJBSY00110;Tianjin Health and Science and Technology Project,No.TJWJ2024ZK001.
BACKGROUND Regulator of G protein signaling(RGS)proteins participate in tumor formation and metastasis by acting on theα-subunit of heterotrimeric G proteins.The speci-fic effect of RGS,particularly RGS4,on the progr...
关键词：Gastric cancer Prognosis Regulator of G protein signaling 4 Focal adhesion kinase Epithelial-mesenchymal transition 
Interfacial Zn^(2+)-solvation regulator towards reversible and stable Zn anode
《Journal of Energy Chemistry》2025年第1期684-692,共9页Miao Zhou Xiongbin Luo Hang Li Shan Guo Zhuang Tong Xiaotao Zhou Xu Li Zhaohui Hou Shuquan Liang Guozhao Fang 
National Natural Science Foundation of China (52301273, 52072411);Science and Technology Innovation Program of Hunan Province (2024RC3222);Key project of scientific research project of Hunan Provincial Department of Education (22A0479);China Postdoctoral Science Foundation (2024M753668);Central South University Innovation-Driven Research Programme (2023CXQD038);Hunan Provincial Postgraduate Research Innovation Programme(CX20240970)。
Aqueous zinc-ion batteries (AZIBs) are fundamentally challenged by the instability of the electrode/electrolyte interface,predominantly due to irreversible zinc (Zn) deposition and hydrogen evolution.Particularly,the ...
关键词：Aqueous zinc-ion batteries Zn^(2+)-solvation structure Interfacial reaction Asymptotic nucleation model Reversible and stable Zn anode 
Montmorillonite modified by composite modifier as a rheological regulator of drilling fluid suitable for ultra-low temperature conditions in Antarctica
《Petroleum Science》2024年第6期4344-4357,共14页Ning Huang Jin-Sheng Sun Jing-Ping Liu Kai-He Lv Zong-Lun Wang Xue-Fei Deng Zhi-Wen Dai Xian-Fa Zhang 
financially supported by the National Natural Science Foundation of China(No.52274021);the National Key Research and Development Program of China(No.2021YFA0719102)。
In order to settle the issues of poor rheology for drilling fluids in Antarctica,it is important to develop an agent that can availably address these challenges.For this reason,a rheological regulator(HSCN)of drilling...
关键词：ANTARCTIC Drilling fluid RHEOLOGY Ultra-low temperature Rheological regulator 
circFKBP8(5S,6)-encoded protein as a novel endogenous regulator in major depressive disorder by inhibiting glucocorticoid receptor nucleus translocation
《Science Bulletin》2024年第24期3826-3831,共6页Jiao Jiao Dandan Xu Yan Kong Yujia Cao Liyuan Wang Yuan Hong Ling Li Chenyu Gao Jing Liu Gaojia Zhang Jiangning Zhou Ji Dai Zhonghua Lu Yan Liu Yutian Wang Zhijun Zhang 
supported by the Chinese Science and Technology Innovation 2030-Major Project(2022ZD0211701 and 2021ZD0200700);the National Natural Science Foundation of China(82130042,81830040 and 82371532);Shenzhen Science and Technology Serial Funds(GJHZ20210705141400002,KCXFZ20211020164543006,JCYJ20220818101615033,ZDSYS202-20606100606014,and KQTD20221101093608028).
Major depressive disorder(MDD)is a debilitating mental health condition that ranks second in the global burden of human diseases[1].Despite extensive research,the etiology and pathogenesis of MDD remain poorly underst...
关键词：GLUCOCORTICOID ENDOGENOUS INHIBITING 
Observational evidence for the AGN wind as a regulator of galaxy evolution
《Science China(Physics,Mechanics & Astronomy)》2024年第12期209-209,共1页Feng Yuan 
The current theory of galaxy formation and evolution faces two significant challenges [1].The first challenge is the strong correlation between the mass of the supermassive black hole and the velocity dispersion of st...
关键词：GALAXY MASSIVE EVOLUTION 
Study on the Control Effect of Chinese Herbal Medicine Regulator on Leaf Spot Nematode Disease of Chloranthus spicatus
《Agricultural Biotechnology》2024年第6期92-98,101,共8页Yuanyuan JIANG Yunxiang HONG Xing SU Mengru DUAN Yujie LI Xinlian WU Bingqian NING Zhibing WAN Ye ZHANG 
Supported by Huangshan Science and Technology Planning Project(2022KN-02);School-level Key Project of Huangshan University(2022XKJZD004);First-class Discipline in Huangshan University(YLXK202101);Key Project of Natural Science Foundation of Department of Education of Anhui Province(2022AH051953);Innovation Training Program(PX-135245491).
[Objectives]This study was conducted to investigate the control of Chinese herbal medicine regulators on leaf spot nematode disease,the main pest of Chloranthus spicatus(Thunb.)Makino.[Methods]C.spicatus plants infect...
关键词：Chloranthus spicatus Leaf spot nematode disease Chinese herbal medicine regulator Physical signs 
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