SPIKE

作品数：309被引量：519H指数：9
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抗SARS-CoV-2变异株的广谱mRNA疫苗RQ3013的临床前研究被引量：5
《Science Bulletin》2023年第24期3192-3206,M0006,共16页谭舒丹 赵京华 胡雪 李玉凤 武子涵 逯国亮 于朝丽 杜彬荷 刘燕 李丽 陈煜琛 李晔 姚艳丰 张小宇 饶具红 高歌 彭云 刘航 袁志明 刘佳 王倩然 胡恒睿 高小博 周辉 俞航 徐颖洁 余巍 冯琳 王曼丽 单超 卢静 林金钟 
supported by Fudan University Special Funds for COVID-19;the National Natural Science Foundation of China(32130063);the National Key Research and Development Program of China(2021YFE0201900 and 2021YFC2301700);China Postdoctoral Science Foundation(2020T130017ZX);the Starry Night Science Fund at Shanghai Institute for Advanced Study of Zhejiang University(SN-ZJU-SIAS-009);the STS Regional Key Project(KFJSTS-QYZD-2021-12-001)from Chinese Academy of Sciences;Hubei Science and Technology Major Project(2021ACB0004)。
全球SARS-CoV-2病毒的不同变异株导致已接种疫苗的人群中突破性感染的比例上升,迫切需要研发更为有效和广谱的COVID-19疫苗.本研究报告了一项mRNA疫苗RQ3013的临床前研究结果,旨在提供对SARS-CoV-2各种变异株(VOCs)的广谱保护.RQ3013疫...
关键词：RQ3013 COVID-19 mRNA vaccine SARS-CoV-2 Chimeric spike 
基于RBD抗原性的五种SARS-CoV-2血清型分类被引量：3
《Science Bulletin》2023年第23期3003-3012,M0005,共11页胡世雄 吴春丽 吴鑫凯 马雪慧 舒畅 陈茜 郑安琪 杨惠婷 陆剑 杜沛 高福 王奇慧 
supported by the National Key R&D Program of China(2022YFC2303403);the National Natural Science Foundation of China(82225021 and 32171428);the CAS Young Scientists in Basic Research(YSBR-010)。
新冠病毒(SARS-CoV-2)的不断进化带来了大量的变异株,特别是Omicron变异株及其众多的亚型.这些变异株表现出越来越强的免疫逃逸能力,使现有疫苗和治疗抗体的效力不断下降.目前,众多变异株已表现出血清交叉中和作用减弱的现象,表明新冠...
关键词：SARS-CoV-2 Serotype classification mRNA vaccine Spike(S) Receptor-binding domain(RBD) 
The numerical simulation of the growth rate of electron-cyclotron maser
《Chinese Science Bulletin》1996年第1期49-54,共6页金声震 赵仁扬 
Project supported by the National Natural Science Foundation of China amd Astronomical Committee of Chinese Academy of Sciences
The spike radiation in the microwave region has been known for a long time as a special radiation which comes from the interaction of waves and nonthermal electron beams in the source region of corona. Many solar radi...
关键词：SPIKE electron-cyclotron MASER simulation. 
The Mechanism of Generation and Variation of Anode Spike Voltage of GTO
《Chinese Science Bulletin》1993年第22期1929-1932,共4页张立 吴爱国 李云德 王江 
Project supported by the National Natural Science Foundation of China.
1 Effects of the Snubber Circuit Figure 1 shows the GTO chopper circuit with inductance load. In Fig. 1 the polarized snubber circuit consists of a resistor R_S, capacitor C_S, and diode V_S. The wiring inductance in ...
关键词：TURN-OFF THYRISTOR (GTO) SPIKE VOLTAGE forward recovery characteristics of the power DIODE 
SOLAR RADIO SPIKE RADIATION COEXISTING WITH A LOOP PROMINENCE SYSTEM
《Chinese Science Bulletin》1991年第22期1890-1893,共4页龚元芳 尚琼珍 胡汉明 吕松泉 李久康 杨荣邦 
Ⅰ. INTRODUCTION In the last decade with the increase of time resolution in observational equipments, solar radio fast time structures were discovered at meter, decimeter, centimeter and millimeter wavebands. This has...
关键词：switch-type SPIKE LOOP PROMINENCE 
A MECHANISM OF SOLAR MICROWAVE MILLISECOND SPIKE BURSTS
《Chinese Science Bulletin》1986年第15期1056-1060,共5页赵仁扬 史建魁 
I.INTRODUCTION In the present paper, we assume that on the way of precipitation of energetic electrons, which are accelerated to 10--100 keV, from the top of flaring loop, a part of them are reflected to form a loss-c...
关键词：SOLAR assume ENERGETIC reflected accelerated LANDAU narrow 圣一 areal 下乙 
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