ACRIDINE

作品数:28被引量:44H指数:5
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相关期刊:《Chemical Research in Chinese Universities》《Journal of Wuhan University of Technology(Materials Science)》《Acta Pharmacologica Sinica》《Chinese Journal of Polymer Science》更多>>
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Novel synthetic acridine-based derivatives as topoisomerase Ⅰ inhibitors被引量:1
《Chinese Chemical Letters》2014年第7期1021-1024,共4页Bin Li Chun-Mei Gao Qin-Sheng Sun Lu-Lu Li Chun-Yan Tan Hong-Xia Liu Yu-Yang Jiang 
the Ministry of Science and Technology of the People’s Republic of China(Nos.2012AA020305and 2011DFA30620);the National Natural Science Foundation of China(Nos.21272134 and 21372141);Shenzhen Sci.&Tech.Bureau(No.JCYJ20120831165730905)for the financial supports
Novel DNA binding agents against topoisomerases are needed for effective treatment of cancers. A series of new acridine-based derivatives 7a-7d were synthesized and their antiproliferative activity against K562 and He...
关键词:ACRIDINE DNA binding agent TOPOISOMERASE ANTICANCER 
Novel synthetic 9-benzyloxyacridine analogue as both tyrosine kinase and topoisomerase I inhibitor被引量:5
《Chinese Chemical Letters》2013年第8期677-680,共4页Xu-Liang Lang Qin-Sheng Sun Yu-Zong Chen Lu-Lu Li Chun-Yan Tan Hong-Xia Liu Chun-Mei Gao Yu-Yang Jiang 
supports from the Ministry of Science and Technology of China(Nos. 2012ZX09506001-010,2012AA020305 and 2011DFA30620);the National Natural Science Foundation of China(Nos.21272134 and 20902053);Shenzhen Sci & Tech Bureau(No. JCYJ20120831165730905)
Multi-target agents against tyrosine kinases and topoisomerases are potentially useful for the effective treatment of cancers.Discovery of new multi-target scaffolds are important for developing such agents. A series ...
关键词:Acridine Topoisomerases Tyrosine kinases Antitumor DNA-binding 
Covalent functionalization of graphene oxide by 9-(4-aminophenyl)acridine and its derivatives被引量:5
《Chinese Chemical Letters》2012年第12期1411-1414,共4页Yi Si Feng Jing Jing Ma Xin Yan Lin Jia Song Zhang Peng Lv Hua Jian Xu Lin Bao Luo 
the financial support from the National Natural Science Foundation of China(Nos.21072040,21071040, 21101051 and 21272050);the Program for New Century Excellent Talents in University of the Chinese Ministry of Education(No.NCET-11-0627)
Graphene/acridine (G-Acr) hybrid structures were synthesized through covalent functionalization of graphene oxide with 9-(4- aminophenyl)acridine (APA) and its derivatives. The G-Act hybrids were characterized b...
关键词:Graphene oxide Covalent functionalization Hybrid material Acridine derivative 
Microwave assisted synthesis of novel Hantzsch 1,4-dihydropyridines,acridine-1,8-diones and polyhydroquinolines bearing the tetrazolo[1,5-α]quinoline moiety and their antimicrobial activity assess被引量:7
《Chinese Chemical Letters》2011年第12期1407-1410,共4页Niraj K.Ladani Divyesh C.Mungra Manish P.Patel Ranjan G.Patel 
Microwave assisted efficient Hantzsch reaction via four-component coupling reactions of tetrazolo[1,5-α]quinoline-4-carbal-dehyde, dimedone/cyclohexane-1,3-dione,ethyl/methyl acetoacetate and ammonium acetate was des...
关键词:Microwave assisted Tetrazolo[1 5-α]quinoline 1 4-Dihydropyridine Acridine-1 8-dione POLYHYDROQUINOLINE Antimicrobial activity 
HPLC of Amino Acids and Oligopeptides by Pre-Column Fluorescence Derivatization with 9-Acridine Formyl Chloride
《Chinese Chemical Letters》1997年第10期875-878,共4页Jin Mao YOU  Xin Jun FAN  Qing Yu OU(Lanzhou Institute of Chemical Physics. Chinese Academy of Sciences 730000) 
A highly sensitive HPLC method for the detection of amino acids and oligopeptides with 9-acridine formyl chloride by pre-column fluorescence derivatization has been developed. Glycine, glycylglycine, histidine, trigly...
关键词:HPLC of Amino Acids and Oligopeptides by Pre-Column Fluorescence Derivatization with 9-Acridine Formyl Chloride 
SYNTHESIS OF 6,7-METHYLENEDIOXY-3-THIA-1(2H,4H)ACRIDONE AND THE RELATED THIA-ACRIDINE-PUSED HETEROCYCLIC COMPOUNDS
《Chinese Chemical Letters》1991年第7期513-514,共2页Ji Rui HOU Jin Jun WANG (Department of Fine Chemistry,Jilin Chemical Industry Institute,Jilin 132022)Gui Ji JIANG Jing Shu LI (Department of Chemistry,Yanbian University,Yanji 133002) 
6,7-Methylenedioxy-3-thia-1(2H,4H)acridone and the related acridine-fused quinolines and pyridines,and also their flavylium-perchlorates were synthesized.The structures of all these compounds prepared are characterize...
关键词:ACRIDONE AND THE RELATED THIA-ACRIDINE-PUSED HETEROCYCLIC COMPOUNDS SYNTHESIS OF 6 7-METHYLENEDIOXY-3-THIA-1 
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