CHLORAMBUCIL

作品数:7被引量:2H指数:1
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相关领域:医药卫生更多>>
相关作者:李功更多>>
相关机构:北京大学更多>>
相关期刊:《Asian Journal of Pharmaceutical Sciences》《Journal of Chinese Pharmaceutical Sciences》《Journal of Biophysical Chemistry》《Chinese Journal of Chemistry》更多>>
相关基金:国家自然科学基金更多>>
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Modification of the alkylating agent chlorambucil with spiropiperazinium salts
《Journal of Chinese Pharmaceutical Sciences》2010年第5期346-352,共7页李功 孙崎 崔景荣 李润涛 
National Natural Science Foundation of China (Grant No.20472008);Fund for Young Teachers of School of Pharmaceutical Sciences,Peking University
In order to improve the antitumor activity and reduce the toxicity of the alkylating agent chlorambucil, a series of spiropiperazinium salts of chlorambucil (8) were designed and synthesized. It was found that compo...
关键词:CHLORAMBUCIL Antitumor activity Spiropiperazinium SAR 
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