云南高校图书馆联盟文献共享服务平台- 李功

李功: 作品数：1被引量：0H指数：0; 导出分析报告; 供职机构：北京大学医学部天然药物及仿生药物国家重点实验室更多>>; 发文主题：SARSALTSCHLORAMBUCILMODIFICATION更多>>; 发文领域：医药卫生更多>>; 发文期刊：《Journal of Chinese Pharmaceutical Sciences》更多>>; 所获基金：国家自然科学基金更多>>

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Modification of the alkylating agent chlorambucil with spiropiperazinium salts: 《Journal of Chinese Pharmaceutical Sciences》2010年第5期346-352,共7页李功孙崎崔景荣李润涛; National Natural Science Foundation of China (Grant No.20472008);Fund for Young Teachers of School of Pharmaceutical Sciences,Peking University; In order to improve the antitumor activity and reduce the toxicity of the alkylating agent chlorambucil, a series of spiropiperazinium salts of chlorambucil （8） were designed and synthesized. It was found that compo...; 关键词：CHLORAMBUCIL Antitumor activity Spiropiperazinium SAR