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Single-cell multi-omics analysis revealing immune features of inactivated COVID-19 vaccination in systemic lupus erythematosus patients
《Science Bulletin》2025年第1期42-46,共5页Yuxuan Zheng Siyuan Wang Xingyu Zhou Shitong Qiao Xin Zhao Yuan Chen Zijun Li Zhanguo Li Xiaolin Sun Shuguang Tan Jing He George Fu Gao 
supported by the National Key Research and Development Program of China(2022YFC2604100,2022YFC2302900,2021YFC2301400,and 2022YFE0131700);National Natural Science Foundation of China(92169208,32222031,82071813,32141004,and 82171775);Peking University People’s Hospital Research and Development Funds(RDGS2022-05);National Postdoctoral Program for Innovative Talents of China(BX20220332)。
Studies have focused on neutralizing antibody titers and T-cell activation induced by vaccination against different SARS-CoV-2strains[1,2].Advanced single-cell technology has allowed for a comprehensive evaluation of ...
关键词：VACCINATION REVEALING TITER 
Impact of various vaccine boosters on neutralization against omicron following prime vaccinations with inactivated or adenovirus-vectored vaccine被引量：3
《Science Bulletin》2022年第13期1326-1330,M0003,共6页Qingrui Huang Jiawei Zeng Qingyun Lang Feng Gao Dejun Liu Siyu Tian Rui Shi Ling Luo Hao Wang Liping Hu Linrui Jiang Yawei Liu Kailiang Li Yunbo Wu Junjie Xu Wenxi Jiang Ning Guo Zhihai Chen Xiaohua Hao Ronghua Jin Jinghua Yan Yufa Sun 
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB29040201);the National Natural Science Foundation of China(NSFC)(81901680)。
SARS-CoV-2 Omicron变异株已在全球范围内广泛传播.包括中国在内的许多国家广泛接种了SARS-CoV-2灭活疫苗(IAV)、重组蛋白疫苗(PRV)和腺病毒载体疫苗(Ad V),以达到群体免疫效果.该研究系统评价了完成不同疫苗全程接种后以及接种不同疫...
关键词：灭活疫苗 不同疫苗 免疫接种 初次免疫 PRV 系统性评价 群体免疫 中和活性 
Inactivated SARS-CoV-2 vaccine does not influence the profile of prothrombotic antibody nor increase the risk of thrombosis in a prospective Chinese cohort被引量：6
《Science Bulletin》2021年第22期2312-2319,M0004,共9页Tingting Liu Jing Dai Zhitao Yang Xiaoqi Yu Yanping Xu Xinming Shi Dong Wei Zihan Tang Guanqun Xu Wenxin Xu Yu Liu Ce Shi Qi Ni Chengde Yang Xinxin Zhang Xuefeng Wang Erzhen Chen Jieming Qu 
supported by the Cultivation Project of Shanghai Major Infectious Disease Research Base(20dz2210500);the Shanghai Key Laboratory of Emergency Prevention,Diagnosis and Treatment of Respiratory Infectious Diseases(20dz2261100);the National Natural Science Foundation of China(81671589 and 81871272).
The presence of antiphospholipid antibodies was shown to be associated with thrombosis in coronavirus disease 2019(COVID-19)patients.Recently,according to reports from several studies,the vaccineinduced immune thrombo...
关键词：Inactivated COVID-19 vaccine Antiphospholipid antibody Anti-PF4-heparin antibody THROMBOSIS THROMBOCYTOPENIA 
Preparation, characterizationand preliminary in vivo stud-ies of inactivated SARS-CoV vaccine
《Chinese Science Bulletin》2003年第23期2621-2625,共5页TANGLin WANGJian QINEde ZHUQingyu YUMan DINGZhifen SHIHuiying CHENGXiaojie WANGCaiping CHANGGuohui LIShuangli ZHANGXumin CHENXishu YUJun CHENZe 
A large quantity of SARS-CoV virus was pro-liferated in Vero cells, inactivated with b-propiolactone, then purified by Sepharose 4FF column chromatography to pre-pare inactivated vaccine. The vaccine was identified by...
关键词：疫苗 非典型肺炎 SARS β-丙内酯 中国 
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