Γ-SECRETASE

作品数：23被引量：59H指数：5
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相关领域：医药卫生更多>>
相关作者：殷莹曹鹏缪凤琴于春泳梁国标更多>>
相关机构：东南大学清华大学第二军医大学台湾大学更多>>
相关期刊：《National Science Review》《Advances in Bioscience and Biotechnology》《Acta Biochimica et Biophysica Sinica》《Medicinal Plant》更多>>
相关基金：国家自然科学基金World Health Organization更多>>
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  • 学科=医药卫生—中医学x
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Potential Mechanism of Huanglian Jiedu Decoction Regulating Iron Homeostasis in NLRP3/IFITM3/γ-secretase Pathway against AD Based on Network Pharmacology
《Medicinal Plant》2025年第2期35-39,共5页Ye CHU Yingyuan QIN Suyi CHEN Linhao LIU Mengjia LI Huanjin HUANG Liuyi WEI Yanyuan ZHOU Linglin CHEN Yifei CHEN 
Supported by National Natural Science Foundation of China(82160832);Natural Science Foundation of Guangxi Zhuang Autonomous Region(2022GXNSFAA035603&2017GXNSFAA198255);the Open Project Program of Guangxi Key Laboratory of Brain and Cognitive Neuroscience,Guilin Medical University(GKLBCN-202206-02);the Fourth Training Plan of Thousands of Young and Mid-aged Mainstay Teachers in Guangxi Colleges and Universities.
[Objectives]To explore the possible targets of Huanglian Jiedu Decoction in NLRP3/IFITM3/γ-secretase pathway through regulating iron homeostasis and the potential mechanism of anti-Alzheimer s disease(AD).[Methods]Fi...
关键词：Huanglian Jiedu Decoction Iron homeostasis Action mechanism Alzheimer's disease(AD) Network pharmacology 
Huannao Yicong Formula (还脑益聪方) Regulates γ-Secretase Activity through APH-1 and PEN-2 Gene Raguiation Pathways in Hippocampus of APP/PS1 Double Transgenic Mice被引量：5
《Chinese Journal of Integrative Medicine》2017年第4期270-278,共9页WANG Zhi-yong LIU Jian-gang WEI Yun LIU Mei-xia WANG Qi LIANG Lin YANG Hui-min LI Hao 
Supported by the National Natural Science Foundation of China(No.81173383 and No.81573819);Beijing Municipal Science and Technology Plan "Ten Disease and Ten Medicine"(No.Z141100002214003)
Objective To observe the effects of Huannao Yicong Formula (还脑益聪方, HYF) on learning and memory and it’s regulating effect on γ-secretase related anterior pharynx defective 1 (APH-1), presenilin enhancer-2 (PEN-...
关键词：Huannao Yicong Formula Alzheimer’s disease Γ-SECRETASE Β-AMYLOID 
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