supported by the Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ13-YQ-101,ZZ16-ND-10-09,ZZ16-ND-10-28);the CACMS Innovation Fund(CI2021A04107),the National Natural Science Foundation of China(U1812403-1);the National Key Research and Development Project(2019YFE0108700,China);the Fundamental Research Funds for the Central Universities(3332022051).
Artemisia annua is the only known plant source of the potent antimalarial artemisinin,which occurs as the low-and high-artemisinin producing(LAP and HAP)chemotypes.Nevertheless,the different mechanisms of artemisinin ...