supported by the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation)Project-ID 259130777-SFB 1177(to CB)。
Misfolding of proteins as well as their aggregation is a major driver of age-related neurodegenerative diseases.Hence,cells have evolved sophisticated protein quality control mechanisms.Mainly the ubiquitin-proteasome...
by the German Research Foundation(DFG,FA 658/3-1).
Parkinson's disease(PD)is diagnosed when patients exhibit bradykinesia with tremor and/or rigidity,and when these symptoms respond to dopaminergic medications.Yet in the last years there was a greater recognition of a...