EXON

作品数：161被引量：414H指数：11
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High-performance single-chip exon capture allows accurate whole exome sequencing using the Illumina Genome Analyzer被引量：3
《Science China(Life Sciences)》2011年第10期945-952,共8页JIANG Tao YANG Lei JIANG Hui TIAN Geng ZHANG XiuQing 
supported by the Chinese Academy of Sciences (Grant Nos.GJHZ0701-6 and KSCX-YWN-023);the National Natural Science Foundation of China (Grant Nos.30725008,90403130,90608010,30221004,90612019 and 30392130);the National Basic Research Program of China (Grant Nos.2007CB815701,2007CB815703 and 2007CB815705)
Here we present an adaptation of NimbleGen 2.1M-probe array sequence capture for whole exome sequencing using the Illumina Genome Analyzer (GA) platform.The protocol involves two-stage library construction.The specifi...
关键词：whole exome sequencing exon capture SNP detection indel detection high-throughput resequencing 
Computational analysis and prediction for exons of PAC579 genomic sequence
《Science China(Life Sciences)》2001年第5期533-540,共8页黄弋 覃文新 万大方 赵新泰 顾健人 
The authors would like to thank Shanghai Genecore Company for finishing all the sequencing work.Thanks are due to Dr. Sun Fenyong, Dr. Ren Gongyi and Dr. Han Liwei for their excellent experimental work. Thanks also go to Prof. Gu Xiaocheng, Luo Jingchu
To isolate the novel genes related to human hepatocellular carcinoma (HCC), we sequenced P1-derived artificial chromosome PAC579 (D17S926 locus) mapped in the minimum LOH (loss of heterozygosity) deletion region of ch...
关键词：computational recognition and prediction EXON genomic sequence. 
Exon structure requirements for yeast tRNA ligase
《Science China(Life Sciences)》1997年第6期665-669,共5页刘建华 金由辛 王德宝 
Project supported by the National Natural Science Foundation of China and Shanghai Research Center of Life Sciences, Chinese Academy of Sciences.
Different nucleotides were introduced into nucleotides 32, 37 and 38 of yeast tRNAphe precursors via oligonucleotide directed mutations. Pre-tRNAs were prepared using T7-transcription in vitro and spliced with the pur...
关键词：pre-tRNAs SPLICING TRNA ENDONUCLEASE TRNA ligase. 
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