Project supported by the National Natural Science Foundation of China(No.29872010);the Natural Science Foundation of Zhejiang Province(No.298067)
The ? ?vicinal dibromo carboxylic acid and its derivatives were debrominated with Sm/HOAc system to afford the corresponding cinnamic acid and its derivatives in good yields under mild conditions.
Reductive debromination of anhydro-6-(R)-hydroxycthyl-6-(R) 7 by zinc in ammonium acetate gave 9 in 81% yield with high stcreosclectivity of 6-(α):6-(β)= 13: 1
The active intermediate'carbon radical' was detected by the spin—trapping reagent (POBN) during the debromination of Ph_2CHBr in the presence of viologen derivatives as electron—transfer catalysts(ETC).
The debromination of diphenyl bromomethane (Ph_2CHBr) using polymers with viologen structure as electron--transfer catalyst (ETC) afforded tetraphenylethane in good yields under het- erophase conditions.
In the presence of equimolar triethylamine,vicinal dibromides were found to be easily debrominated by dibutyl telluride,forming the co- rresponding olefins.