There is a considerable demand but limited supply for hematopoietic stem cells (HSCs) in clinics. To meet clinical needs of HSCs, new efforts focus on de novo HSCs generation from pluripotent stem cells (PSCs). Althou...
supported by the National Key Research and Development Program on Modernization of Traditional Chinese Medicine(No.2022YFC3502100);the National Natural Science Foundation of China(No.82274186);the National High-Level Talents Special Support Program;the Young Talents Promotion Project of China Association of Traditional Chinese Medicine(No.2020-QNRC2-01);the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(No.ZYYCXTD-C-202006).
Liver fibrosis is characterized by chronic inflammatory responses and progressive fibrous scar formation.Macrophages play a central role in the pathogenesis of hepatic fibrosis by reconstructing the immune microenviro...