MACROLIDE

作品数：32被引量：76H指数：4
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相关领域：医药卫生理学更多>>
相关作者：夏曦李少丽李建成丁双阳江海洋更多>>
相关机构：中国农业大学首都儿科研究所中国科学院更多>>
相关期刊：《Acta Pharmacologica Sinica》《Chinese Medical Journal》《Advances in Microbiology》《World Journal of Pediatrics》更多>>
相关基金：国家自然科学基金北京市自然科学基金“十一五”国家科技支撑计划The Royal Society更多>>
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Synthesis of novel 15-membered macrolide dimers
《Chinese Chemical Letters》2009年第8期931-934,共4页Shu Tao Ma Rui Xin Ma Rui Qing Xian Bo Jiao 
supported by the National Natural Science Foundation of China(No.2087208 1);Natural Science Foundation of Shandong(No.Y2006C3 1);Shandong Science and Technology Promotion Project(No.2005GG3202098).
A series of novel dimers of 15-membered macrolides was synthesized and evaluated. The dimers exhibited excellent activity against erythromycin-susceptible S. pneumonia, but did not show any improved activity against e...
关键词：MACROLIDE Azithromycin derivatives D/mers SYNTHESIS 
Synthesis of novel 15-membered macrolide derivatives被引量：2
《Chinese Chemical Letters》2008年第4期409-411,共3页Rui Qing Xian Shu Tao Ma Bo Jiao 
supported by NNSFC(No.20372043),Shandong Science and Technology Promotion Project(No.2005GG3202098);Natural Science Foundation of Shandong Province(No.Y2006C31).
In order to develop new antibiotics effective against resistant bacteria,a series of novel 15-membered macrolide derivatives were designed and synthesized by the modification of hydroxyl groups at C-11,C-12 and C-4＂ ...
关键词：MACROLIDE Azithromycin derivatives SYNTHESIS 4＂-Carbamate derivatives 
A Novel Oxidative N-Demethylation of 12-Membered Macrolide with Lead Tetraacetate
《Chinese Chemical Letters》2006年第1期9-11,共3页Wei Ge ZHANG Ying Hua JIN Ping QI Kai BAO Jin Guang LIN Nai Li WANG Xin Shen YAO 
Reaction of 12-membered macrolide 1 with lead tetraacetate in dichloromethane afforded an unexpected, novel oxidative N-demethyl product 3.
关键词：Oxidative N-demethylation 12-membered macrolide lead tetraacetate. 
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