supported by JSPS KAKENHI Grant Number[22K16027];The Hori Sciences and Arts Foundation Grant Number[JOSE205003].
Introduction Immune checkpoint inhibitors(ICIs)have shown clinical efficacy in the treatment of various malignancies[1,2].The grading system for ICI-associated pancreatitis is based on elevated levels of pancreatic en...
Coronary ostial stenosis after surgical aortic valve replacement (SAVR) is a rare but potentially fatal complication. Surgeons must have a high level of vigilance regarding the presentation of acute myocardial ischemi...
A novel coronavirus disease 2019(COVID-19)is a progressive viral disease that affected people around the world with widespread morbidity and mortality.Patients with COVID-19 infection typically had pulmonary manifesta...
supported by the Natural Science Foundation of China (Grant numbers:82025034 and 81973392);the National Key Research and Development Program (Grant number:2017YFE0109900, China);the Shenzhen Science and Technology Program (Grant number:KQTD20190929174023858, China);the Natural Science Foundation of Guangdong (Grant number:2017A030311018, China);the 111 project (Grant number:B16047, China);the Key Laboratory Foundation of Guangdong Province (Grant number:2017B030314030, China);the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program (Grant number:2017BT01Y093, China);the National Engineering and Technology Research Center for New drug Druggability Evaluation (Seed Program of Guangdong Province, Grant number:2017B090903004, China)。
The constitutive androstane receptor(CAR, NR3 I1) belongs to nuclear receptor superfamily.It was reported that CAR agonist TCPOBOP induces hepatomegaly but the underlying mechanism remains largely unknown. Yes-associa...
supported by the Key Area R&D Program of Guangdong Province(No.2019B020227005);National Key Research and Development Program of China(No.2016YFC1301202)。
Background Non-dipping blood pressure(BP)pattern is a potential risk factor contributing to cardiac geometry change.Relationship between BP pattern and left atrium(LA)enlargement besides left ventricle(LV)structural c...
PRKAG2 cardiac syndrome(PS)is a rare inherited disease due to PRKAG2 gene mutation and characterized by Wolff-Parkinson-White syndrome(WPWs),conduction system lesions and myocardial hypertrophy.It can also lead to ser...
Background: Small aortic annulus during aortic valve replacement can lead to implanting a smaller sized valve compared to the body surface area thereby causing patient prosthesis mismatch. Various aortic root enlargem...
Objectives: According to the International Registry of Acute Aortic Dissection, >70% of patients with type-B aortic dissection (AD) have delayed aortic growth. The objective of this study was to investigate the morpho...
To evaluate factors that influence the diagnostic accuracy of endoscopic ultrasound (EUS)-guided tissue acquisition for lymph node enlargement in the absence of an on-site pathologist. METHODSA retrospective analysis ...
Objective To report five cases of isolated Ig G4-related sclerosing cholangitis(IAC)and to summarize their clinical characteristics and the differential diagnosis.Methods The clinical data of five patients with isolat...